PMID: 8610505Jan 1, 1995Paper

Reducing arrhythmogenic effects in the isolated heart enriching roentgen contrast media with electrolytes. Survey and present state

Acta Radiologica. Supplementum
J Besjakov, L Bååth

Abstract

A review of the literature on the effects of adding electrolytes to ionic as well as nonionic contrast media (CM) in the isolated heart model reveals that both ionic and nonionic CM favor from such addtion, if the added electrolytes are balanced with respect to each other. By enriching nonionic monomeric as well as dimeric CM with such a balanced electrolyte solution, the risk of ventricular fibrillation is reduced and myocardial contractibility is improved compared to nonionic CM without such enrichment. The new nonionic dimer iodixanol is slightly hypotonic to plasma in concentrations suitable for coronary arteriography. The water solution of iodixanol therefore contains an osmotic space in which electrolytes can be added, therby making it isotonic with plasma.

References

May 1, 1978·Investigative Radiology·K R ThomsonH W Fischer
May 1, 1991·Progress in Cardiovascular Diseases·M R Franz
Jan 1, 1985·Investigative Radiology·T Almén
Mar 1, 1987·Drug Intelligence & Clinical Pharmacy·J G Gums
Apr 1, 1972·The American Journal of Roentgenology, Radium Therapy, and Nuclear Medicine·A L SimonE C Lasser
Nov 1, 1971·The American Journal of Roentgenology, Radium Therapy, and Nuclear Medicine·C F SnyderK Amplatz
Oct 1, 1984·British Heart Journal·R Hayward, P Dawson
Jan 1, 1982·Investigative Radiology·B TrägårdhP R Lynch
Jan 1, 1964·Radiology·G G GENSINI, S DIGIORGI

❮ Previous
Next ❯

Related Concepts

Related Feeds

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.