Reducing arthritis fatigue impact: two-year randomised controlled trial of cognitive behavioural approaches by rheumatology teams (RAFT)

Annals of the Rheumatic Diseases
Sarah HewlettRAFT Study Group

Abstract

To see if a group course delivered by rheumatology teams using cognitive-behavioural approaches, plus usual care, reduced RA fatigue impact more than usual care alone. Multicentre, 2-year randomised controlled trial in RA adults (fatigue severity>6/10, no recent major medication changes). RAFT (Reducing Arthritis Fatigue: clinical Teams using CB approaches) comprises seven sessions, codelivered by pairs of trained rheumatology occupational therapists/nurses. Usual care was Arthritis Research UK fatigue booklet. Primary 26-week outcome fatigue impact (Bristol RA Fatigue Effect Numerical Rating Scale, BRAF-NRS 0-10). Intention-to-treat regression analysis adjusted for baseline scores and centre. 308/333 randomised patients completed 26 week data (156/175 RAFT, 152/158 Control). Mean baseline variables were similar. At 26 weeks, the adjusted difference between arms for fatigue impact change favoured RAFT (BRAF-NRS Effect -0.59, 95% CI -1.11 to -0.06), BRAF Multidimensional Questionnaire (MDQ) Total -3.42 (95% CI -6.44 to -0.39), Living with Fatigue -1.19 (95% CI -2.17 to -0.21), Emotional Fatigue -0.91 (95% CI -1.58 to -0.23); RA Self-Efficacy (RASE, +3.05, 95% CI 0.43 to 5.66) (14 secondary outcomes unchanged). Effects persisted ...Continue Reading

References

Jun 1, 1983·Acta Psychiatrica Scandinavica·A S Zigmond, R P Snaith
Feb 1, 1980·Arthritis and Rheumatism·R F MeenanJ H Mason
Aug 6, 2005·Arthritis and Rheumatism·S J FarrowD L Scott
Oct 7, 2005·Arthritis and Rheumatism·Sarah HewlettMaggie Hehir
Jul 12, 2007·Multiple Sclerosis : Clinical and Laboratory Research·D KosE Kerckhofs
Jul 31, 2007·International Journal of Nursing Studies·Han Repping-WutsTheo van Achterberg
Mar 25, 2008·Journal of Clinical Epidemiology·Jacques PouchotMatthew H Liang
Feb 27, 2009·Journal of Advanced Nursing·Han Repping-WutsTheo van Achterberg
Apr 7, 2009·Annals of the Rheumatic Diseases·R SerorP Ravaud
Feb 26, 2010·The American Journal of Drug and Alcohol Abuse·Arin M Connell
Sep 8, 2010·Rheumatology·Sarah HewlettJohn Kirwan
Jan 8, 2013·Clinical Rheumatology·Caroline FeldthusenUNKNOWN University of Gothenburg Centre for Person-Centred Care (GPCC)
Jan 22, 2013·Arthritis Care & Research·Stephanie NikolausMart A F J van de Laar
Jun 25, 2013·Journal of the Neurological Sciences·Y C LearmonthR W Motl
Aug 27, 2013·The Cochrane Database of Systematic Reviews·Fiona CrampRobin Christensen
Dec 3, 2014·Patient Education and Counseling·Andrew TurnerClaire Bourne
Oct 29, 2015·RMD Open·Hanna W van SteenbergenAnnette H M van der Helm-van Mil
Apr 9, 2016·Joint, Bone, Spine : Revue Du Rhumatisme·Tania GuduLaure Gossec
Jun 9, 2016·The Cochrane Database of Systematic Reviews·Celia AlmeidaRobin Christensen

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Nov 10, 2021·Scandinavian Journal of Occupational Therapy·Margaret L SøvikTina Taule

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Methods Mentioned

BETA
cognitive behavioural therapy
cognitive

Clinical Trials Mentioned

ISRCTN52709998

Software Mentioned

STATA

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