PMID: 3756797Oct 15, 1986Paper

Reducing diagnostic delay in breast cancer. Possible therapeutic implications. GIVIO (Interdisciplinary Group for Cancer Care Evaluation) Italy

Cancer

Abstract

A detailed examination of the diagnostic process of 1110 newly diagnosed breast cancer patients first seen at 63 Italian general hospitals showed that 36% of them were diagnosed more than 3 months after the appearance of the first symptom. Whereas 17% (108/633) of the women with less than or equal to 3 months delay were Stage III and IV, the corresponding proportion among women with greater than 3 months delay was 32% (101/320), suggesting that 15% of advanced cases can be attributed to diagnostic delay. A 9% gain in survival at 5 years (66% vs. 57%) could be postulated if reported figures on mortality by stage are applied to our patients with less than or equal to 3 months delay compared to those with greater than 3 months. Moreover, examining the two components of delay (first symptom-first visit and first visit-final diagnosis) our data suggest that the potential benefits of timely presentation were, for some patients, cancelled by delays arising in the health care system. Breast self-examination (BSE) was practiced by 34% of the total population, but only 9% did it on a regular monthly basis. Although any type of BSE (regular and irregular) was associated with a smaller primary at presentation, a limited benefit of the proc...Continue Reading

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Citations

Mar 17, 2000·Journal of Psychosomatic Research·C C BurgessM A Richards
Aug 21, 2001·Breast Cancer Research and Treatment·M MontellaG D'Aiuto
Apr 14, 2011·Journal of Women's Health·Rose C MalyAmardeep Thind
Jan 12, 2000·American Journal of Public Health·A R FolsomC P Hong
Mar 27, 2001·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·M MontellaP Silvestra
Apr 17, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Volker ArndtHermann Brenner
Jan 12, 2000·Medical Care·P ThongsuksaiH Sriplung
Mar 28, 2007·Cancer Control : Journal of the Moffitt Cancer Center·Cynthia M MojicaNinez A Ponce
Jul 22, 2010·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Roshan BastaniPatricia A Ganz

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