PMID: 16501712Feb 28, 2006Paper

Reducing diarrhoea in Guatemalan children: randomized controlled trial of flocculant-disinfectant for drinking-water

Bulletin of the World Health Organization
Tom M ChillerS P Luby

Abstract

To examine the effect of a new point-of-use treatment for drinking-water, a commercially developed flocculant-disinfectant, on the prevalence of diarrhoea in children. We conducted a randomized controlled trial among 514 rural Guatemalan households, divided into 42 neighbourhood clusters, for 13 weeks, from 4 November 2002 through 31 January 2003. Clusters assigned to water treatment with the flocculant-disinfectant were compared with those using their usual water-handling practices. The longitudinal prevalence of diarrhoea was calculated as the proportion of total days with diarrhoea divided by the total number of days of observation. The prevalence of diarrhoea was compared using the Wilcoxon rank-sum test. The 1702 people in households receiving the disinfectant had a prevalence of diarrhoea that was 40% lower than that among the 1699 people using standard water-handling practices (0.9% versus 1.5%; P = 0.001). In households using the flocculant-disinfectant, children < 1 year of age had a 39% lower prevalence of diarrhoea than those in households using their standard practices (3.7% versus 6.0%; P = 0.005). In settings where families rarely treat drinking-water, we introduced a novel flocculant-disinfectant that reduced the...Continue Reading

Citations

Aug 5, 2011·The American Journal of Tropical Medicine and Hygiene·Rachel PeletzThomas Clasen
Jan 10, 2012·Annual Review of Public Health·Joseph N S EisenbergKatherine F Shields
Jun 5, 2015·Journal of Water and Health·Hussein MohamedSteven Mbuligwe
Oct 22, 2015·The Cochrane Database of Systematic Reviews·Thomas F ClasenSandy Cairncross
Nov 2, 2016·Journal of Nursing Scholarship : an Official Publication of Sigma Theta Tau International Honor Society of Nursing·Kim L LarsonDiego Carreño
Sep 8, 2016·BMC Infectious Diseases·Charles NjugunaSamuel Kariuki
Apr 6, 2011·BMC Public Health·Andri ChristenDaniel Mäusezahl
Nov 17, 2017·BMC Public Health·Nazia DarveshUNKNOWN Social Determinants of Health Study Team
Mar 24, 2006·Tropical Medicine & International Health : TM & IH·Stephen P LubyRobert M Hoekstra
Jun 22, 2012·Water Quality, Exposure, and Health·Laura M NormanSaskia Van Rijn
Sep 10, 2021·Environmental Science & Technology·Daniel W SmithJennifer Davis
Oct 12, 2010·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Wences ArveloAnna Bowen

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