PMID: 7539642Apr 1, 1995Paper

Reduction effect of theanine on blood pressure and brain 5-hydroxyindoles in spontaneously hypertensive rats

Bioscience, Biotechnology, and Biochemistry
H YokogoshiN Takeuchi

Abstract

The effect of theanine, one of the components of green tea, on the blood pressure and brain 5-hydroxyindoles in spontaneously hypertensive rats (SHR) and Wistar Kyoto rats (WKY) was investigated by intraperitoneally administering theanine. The effect of glutamine, which is structurally similar to theanine, was also examined. When SHR were injected with various amounts of theanine (0, 500, 1000, 1500, and 2000 mg/kg), the change was dose-dependent, and a significant decrease in blood pressure was observed with the high doses (1500 and 2000 mg/kg). A dose of 2000 mg/kg of theanine did not alter the blood pressure of WKY, while the same dose to SHR decreased it significantly. On the other hand, glutamine administration to SHR did not change either the blood pressure or the heart rate. The brain 5-hydroxyindole level was significantly decreased by theanine administration to both WKY and SHR, the decrease being dose-dependent.

Citations

Dec 12, 2012·Bioscience, Biotechnology, and Biochemistry·Sachiko YamamotoMakoto Ushimaru
Dec 8, 2009·Bioscience, Biotechnology, and Biochemistry·Koichiro Miyake, Shingo Kakita
Oct 31, 2012·Journal of Physiological Anthropology·Ai YotoHidehiko Yokogoshi
Mar 17, 2012·European Journal of Nutrition·Kim ZarseMichael Ristow
Jul 5, 2005·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Raymond CooperDorothy M Morré
Apr 9, 2013·Nutrition Research Reviews·C F HaskellD O Kennedy
Sep 20, 2012·Oxidative Medicine and Cellular Longevity·Yuqing DongSige Zou
Nov 2, 2011·International Journal of Food Sciences and Nutrition·Raymond Cooper
Nov 29, 2013·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Hui YangLei Xue
Jul 24, 2012·The Journal of Nutritional Biochemistry·Jamila H SiamwalaSuvro Chatterjee
Feb 15, 2012·Journal of Gerontological Nursing·Jung Tae Son, Eunjoo Lee
Mar 24, 2009·The Journal of Clinical Hypertension·Ralph E WatsonVed V Gossain
May 26, 2004·Neuroscience Letters·Nobuaki EgashiraMichihiro Fujiwara
May 2, 2006·Journal of the American College of Surgeons·Bauer E SumpioQuan Hai Chen
Jun 9, 2006·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·J F BorzellecaW Hall
Jul 21, 2015·Critical Reviews in Food Science and Nutrition·Duygu Türközü, Nevin Şanlier
Apr 15, 2015·Biotechnology Advances·Wanmeng MuBo Jiang
Aug 26, 2006·Biological Psychology·Kenta KimuraHideki Ohira
Oct 5, 2016·Journal of Clinical Biochemistry and Nutrition·Mika TakeshimaMasato Asanuma
Dec 25, 2002·Biological & Pharmaceutical Bulletin·Takami Kakuda
Apr 25, 2017·Complementary Therapies in Medicine·Chi-Wei ChangWei-Kung Wang
Nov 21, 2002·Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan·Yasuyuki SadzukaTakashi Sonobe
Jul 19, 2014·Journal of Physiological Anthropology·Ai YotoHidehiko Yokogoshi
Aug 21, 2007·Phytotherapy Research : PTR·Nobuaki EgashiraMichihiro Fujiwara
Jun 11, 1999·Bioscience, Biotechnology, and Biochemistry·T TerashimaH Yokogoshi
May 17, 2008·Applied Biochemistry and Biotechnology·Chih-Peng HungLong-Liu Lin

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.