Reduction in MRSA environmental contamination with a portable HEPA-filtration unit

The Journal of Hospital Infection
T C Boswell, P C Fox

Abstract

There is renewed interest in the hospital environment as a potentially important factor for cross-infection with methicillin-resistant Staphylococcus aureus (MRSA) and other nosocomial pathogens. The aim of this study was to evaluate the effectiveness of a portable high-efficiency particulate air (HEPA)-filtration unit (IQAir Cleanroom H13, Incen AG, Goldach, Switzerland) at reducing MRSA environmental surface contamination within a clinical setting. The MRSA contamination rate on horizontal surfaces was assessed with agar settle plates in ward side-rooms of three patients who were heavy MRSA dispersers. Contamination rates were measured at different air filtration rates (60-235 m(3)/h) and compared with no air filtration using Poisson regression. Without air filtration, between 80% and 100% of settle plates were positive for MRSA, with the mean number of MRSA colony-forming units (cfu)/10-h exposure/plate ranging from 4.1 to 27.7. Air filtration at a rate of 140 m(3)/h (one patient) and 235 m(3)/h (two patients), resulted in a highly significant decrease in contamination rates compared with no air filtration (adjusted rate ratios 0.037, 0.099 and 0.248, respectively; P < 0.001 for each). A strong association was demonstrated b...Continue Reading

References

Sep 1, 1991·The Journal of Hospital Infection·E P Moore, E W Williams
Apr 1, 1981·The Journal of Hygiene·J C LawrenceM D Wilkins
Jul 1, 1995·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·W A RutalaD J Weber
Jul 1, 1993·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·M C LaytonJ E Patterson
Mar 15, 1996·Annals of Internal Medicine·R J SherertzJ M Gwaltney
Jun 1, 1996·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·V G LooH G Robson
Sep 1, 1996·Journal of the Air & Waste Management Association·S Miller-LeidenJ M Macher
Oct 6, 1997·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·J M BoyceT King
Mar 26, 1998·The Journal of Hospital Infection·D BlytheA Galloway
Aug 27, 1999·The Journal of Hospital Infection·D Talon
Sep 25, 2001·The Journal of Hospital Infection·A RamplingA J Cornaby
Jan 8, 2003·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·John M BoyceUNKNOWN Healthcare Infection Control Practices Advisory Committee. Society for Healthcare Epidemiology of America. Association for P

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Citations

Feb 15, 2008·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·N Cimolai
Feb 17, 2009·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Ivanka Matouskova, Vladimir Janout
Oct 11, 2012·Industrial Health·Sabrina S JedlickaCharles E Lyman
Aug 14, 2012·Burns : Journal of the International Society for Burn Injuries·Frédéric BarbutJonathan A Otter
Mar 1, 2007·American Journal of Infection Control·Luke Curtis
Oct 21, 2014·Patient Safety in Surgery·David M Tsai, Edward J Caterson
Jan 31, 2015·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·C W SadlerK Byth
Jun 23, 2016·Health Services Research·Torsten Oliver SalgeJeannie P Cimiotti
Jul 21, 2017·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Clyde D FordFinn Bo Petersen
Oct 14, 2008·Journal of Burn Care & Research : Official Publication of the American Burn Association·Luke Curtis
Jul 10, 2020·Journal of Occupational and Environmental Hygiene·Rachael M Jones
Aug 28, 2020·Environmental Science & Technology·Ehsan S MousaviJodi D Sherman
Apr 6, 2021·Energy and Buildings·Marietta M SquireTakeru Igusa
Jul 28, 2021·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Luke Curtis

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