Reduction in the incidence of alveolar osteitis in patients treated with the SaliCept patch, containing Acemannan hydrogel

Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
Miles R PoorAnne S Poor

Abstract

In the present study, we compared the incidence of alveolar osteitis (AO) in patients treated with either clindamycin-soaked Gelfoam (Pharmacia and Upjohn Co, Kalamazoo, MI) or SaliCept Patches (Carrington Laboratories, Inc, Irving, TX). The SaliCept Patch is a freeze-dried pledget that contains Acemannan Hydrogel (Carrington Laboratories) obtained from the clear inner gel of Aloe vera L. A retrospective evaluation was performed of the records of 587 patients (1,031 sockets) whose extraction sites had been treated with clindamycin-soaked Gelfoam. A prospective trial was conducted in which 607 patients (1,064 sockets) had 2 SaliCept Patches placed immediately after extraction. The same surgeon treated all patients. Analysis restricted to mandibular third molar sites showed that 78 of 975 sites (8.0%) in the Gelfoam group developed AO, whereas only 11 of 958 sites (1.1%) in the SaliCept group developed AO (P <.0001). Further analysis of all extraction sites revealed that the incidence of AO in the Gelfoam group was 7.6% compared with 1.1% in the SaliCept-treated group (P <.0001). The study results suggest that the SaliCept Patch significantly reduces the incidence of AO compared with clindamycin-soaked Gelfoam.

Citations

Apr 9, 2009·Bioscience, Biotechnology, and Biochemistry·Norimitsu TamuraMakoto Hattori
Aug 9, 2011·Vojnosanitetski pregled. Military-medical and pharmaceutical review·Goran JovanovićSimona Stojanović
Jul 3, 2018·Journal of the Korean Association of Oral and Maxillofacial Surgeons·Mohammad Ali SaghiriNader Sheibani
May 12, 2012·International Journal of Dentistry·Abbas HaghighatHossein Goroohi
May 1, 2010·International Journal of Clinical Pediatric Dentistry·Neha Gupta Girish
Sep 12, 2020·Oral and Maxillofacial Surgery Clinics of North America·Patrick J Louis
Apr 16, 2021·Journal of Dental Sciences·Ngoc Bao VuPasutha Thunyakitpisal
Jan 4, 2012·Carbohydrate Polymers·Mayank ThakurShilpi Bhargava
Mar 15, 2011·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Göksel Şimşek KayaMetin Güngörmüş

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