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Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin

The New England Journal of Medicine

Feb 8, 2002

W C KnowlerDiabetes Prevention Program Research Group

Abstract

Type 2 diabetes affects approximately 8 percent of adults in the United States. Some risk factors--elevated plasma glucose concentrations in the fasting state and after an oral glucose load, overweight, and a sedentary lifestyle--are potentially reversible. We hypothesized that modifyin...read more

Mentioned in this Paper

Patient Non-Compliance
Diabetes Mellitus, Non-Insulin-Dependent
Metformin
Exercise, Isometric
Energy Intake
Body Mass Index Procedure
Plasma Glucose Measurement
Overweight
Life Style Induced Illness
Double-Blind Method
497
128
36
4546
5
Paper Details
References
  • References19
  • Citations6715
12
  • References19
  • Citations6715
12345...

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Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin

The New England Journal of Medicine

Feb 8, 2002

W C KnowlerDiabetes Prevention Program Research Group

PMID: 11832527

DOI: 10.1056/nejmoa012512

Abstract

Type 2 diabetes affects approximately 8 percent of adults in the United States. Some risk factors--elevated plasma glucose concentrations in the fasting state and after an oral glucose load, overweight, and a sedentary lifestyle--are potentially reversible. We hypothesized that modifyin...read more

Mentioned in this Paper

Patient Non-Compliance
Diabetes Mellitus, Non-Insulin-Dependent
Metformin
Exercise, Isometric
Energy Intake
Body Mass Index Procedure
Plasma Glucose Measurement
Overweight
Life Style Induced Illness
Double-Blind Method
497
128
36
4546
5

Feeds With Similar Papers

Type 2 Diabetes

This feed focuses on Type 2 Diabetes, a disease where the body doesn’t produce or respond to insulin anymore, leading to abnormal glucose levels in the blood.

NEJM eTOC

The New England Journal of Medicine (NEJM) is a medical journal published by the Massachusetts Medical Society. Discover the latest research from NEJM here.

Related Papers

The New England Journal of Medicine

Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance

The New England Journal of MedicineMay 3, 2001
Jaakko TuomilehtoFinnish Diabetes Prevention Study Group
Paper Details
References
  • References19
  • Citations6715
12
  • References19
  • Citations6715
12345...

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