PMID: 6159950Dec 8, 1980Paper

Reduction of [3H]muscimol binding sites in rat dorsal spinal cord after neonatal capsaicin treatment

Brain Research
E Singer, P Placheta

Abstract

Two-day-old rats were pretreated with 50 mg/kg of capsaicin. After 3--4 months, specific binding of [3H]muscimol and [3H]strychnine was measured in membrane preparations from dorsal spinal cord. A 20-30% decrease of the number of [3H]muscimol binding sites was observed after capsaicin treatment. In contrast, [3H]strychnine binding was unchanged. The results provide indirect evidence for a presynaptic location of GABA receptors on capsaicin-sensitive primary afferent neurons.

References

Sep 1, 1979·Naunyn-Schmiedeberg's Archives of Pharmacology·R GamseF Lembeck
Dec 1, 1975·The Journal of Comparative Neurology·B J McLaughlinJ Y Wu
Oct 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·A B Young, S H Snyder
Jan 1, 1973·The Journal of Physiology·J L Barker, R A Nicoll
Mar 31, 1980·Brain Research·J I NagyH I Yamamura
Jun 1, 1952·The Journal of Comparative Neurology·B REXED

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Citations

Aug 27, 1993·Brain Research·J M Castro-LopesA Coimbra
Jan 1, 1983·Pharmacology, Biochemistry, and Behavior·R J BodnarG Nilaver
Jan 1, 1988·Pharmacology & Therapeutics·L A Chahl
Dec 1, 1984·Brain Research·L C Russell, K J Burchiel
Jun 1, 1997·Brain Research. Brain Research Reviews·R E Coggeshall, S M Carlton
Sep 21, 2000·The European Journal of Neuroscience·S TowersN G Bowery
Jan 1, 1992·The European Journal of Neuroscience·J. M. Castro-LopesA. Coimbra
Jan 31, 2015·PloS One·Sang Hoon LeeJun Ho Jang
Oct 1, 1982·Critical Reviews in Toxicology·Y MonsereenusornP D Pezalla
Feb 10, 2018·Seminars in Immunopathology·Linda S SorkinTony L Yaksh
Aug 24, 2013·Journal of Neurophysiology·Emanuel Loeza-AlcocerRodolfo Delgado-Lezama
Nov 7, 2015·Pain·Mariana Bravo-HernándezVinicio Granados-Soto
Feb 1, 1983·Pain·M Fitzgerald

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