Reduction of chlortetracycline-resistant Escherichia coli in weaned piglets fed fermented liquid feed

Anaerobe
Yuri KobashiHiroo Uchiyama

Abstract

We investigated the change in chlortetracycline resistance in 360 Escherichia coli strains separated from the feces of piglets fed fermented liquid feed (FLF) in comparison with those fed dry feed (control). The total amount of lactic acid bacteria in feces was 8.77 x 10(8) CFU/g DM at weaning, which increased to 1.23 x 10(12) CFU/g DM (FLF) at 28 days after weaning (P<0.001). As a result of the antibiotic susceptibility test, almost all isolates were chlortetracycline-resistant (CTCR) until 14 days after weaning both in the FLF and control groups. At 28 days, the CTCR E. coli decreased to 22.2% in the FLF group, while the proportion of resistant bacteria was 88.9% in the control group. In addition, as a result of the gene analysis, it was clarified that there is a relation between the decrease in the minimum inhibitory concentration values and the possession rate of the tetracycline-resistance gene tet(A), tet(B) and tet(D). These results show that FLF caused an increase in the number of lactic acid bacteria in the intestines, and suggested that the feeding of FLF can possibly reduce antibiotic-resistance bacteria.

References

Aug 18, 2001·Journal of Nutritional Science and Vitaminology·Y OhashiK Ushida
Aug 22, 2001·Molecular and Cellular Probes·L K NgM Mulvey
Oct 7, 2004·Applied and Environmental Microbiology·Joshua R HayesSam W Joseph
Mar 31, 2005·Veterinary Immunology and Immunopathology·L ScharekK Tedin
Oct 6, 2005·The Journal of General and Applied Microbiology·Ryo InoueKazunari Ushida
Jul 18, 2006·Current Drug Targets·Gabriella SpenglerJoseph Molnár

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Citations

Jan 11, 2011·Archives of Animal Nutrition·Joris A M MissottenNoël A Dierick
Apr 28, 2009·Anaerobe·Kiyoshi TajimaTomoyuki Kawashima

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