Reduction of hypoglycaemic events with a behavioural intervention: a randomized clinical trial for paediatric patients with Type 1 diabetes mellitus

Diabetic Medicine : a Journal of the British Diabetic Association
B T GeeAiyi Liu

Abstract

To determine if a low-intensity, clinic-integrated behavioural intervention reduced the incidence of hypoglycaemic events in children with Type 1 diabetes. A total of 390 families with children with Type 1 diabetes were enrolled in a 2-year, randomized clinical trial of a behavioural intervention. The intervention was designed to improve diabetes management practices by targeting the family's diabetes problem-solving skills. Hypoglycaemic events were categorized in two groups: those treated by oral ingestion and those treated by parenteral therapy. Events were self-reported by participants at each clinic visit, which occurred approximately every 3-4 months. Analyses included two-sample t-tests, the mean cumulative function test, and the Cox proportional hazards model for recurrent events to compare the incidence between groups. Across the entire 2-year study period, the incidence of hypoglycaemic events treated by oral ingestion of glucose-rich foods and events requiring parenteral therapy did not significantly differ between study conditions; however, during the second year of participant enrolment, the incidence of events treated by oral ingestion in the intervention group was 13.6 per 100 person-years compared with 27.3 per ...Continue Reading

References

Jul 24, 1986·The New England Journal of Medicine·S A AmielW V Tamborlane
Mar 5, 2002·Journal of Pediatric Endocrinology & Metabolism : JPEM·Jill Hamilton, Denis Daneman
Jul 31, 2002·Diabetic Medicine : a Journal of the British Diabetic Association·Barbara J AndersonL M B Laffel
Apr 25, 2003·The Journal of Pediatrics·Lori M B LaffelBarbara J Anderson
May 27, 2003·Diabetes Care·Philip E CryerHarry Shamoon
Sep 13, 2007·Journal of Pediatric Psychology·Vicki S HelgesonDorothy Becker
Mar 9, 2013·Pediatric Diabetes·Eda CengizUNKNOWN T1D Exchange Clinic Network

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Citations

Feb 14, 2017·Diabetic Medicine : a Journal of the British Diabetic Association·R I G Holt

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