Reduction of Onset Delay in Functional Near-Infrared Spectroscopy: Prediction of HbO/HbR Signals

Frontiers in Neurorobotics
Amad Zafar, Keum-Shik Hong

Abstract

An intrinsic problem when using hemodynamic responses for the brain-machine interface is the slow nature of the physiological process. In this paper, a novel method that estimates the oxyhemoglobin changes caused by neuronal activations is proposed and validated. In monitoring the time responses of blood-oxygen-level-dependent signals with functional near-infrared spectroscopy (fNIRS), the early trajectories of both oxy- and deoxy-hemoglobins in their phase space are scrutinized. Furthermore, to reduce the detection time, a prediction method based upon a kernel-based recursive least squares (KRLS) algorithm is implemented. In validating the proposed approach, the fNIRS signals of finger tapping tasks measured from the left motor cortex are examined. The results show that the KRLS algorithm using the Gaussian kernel yields the best fitting for both ΔHbO (i.e., 87.5%) and ΔHbR (i.e., 85.2%) at q = 15 steps ahead (i.e., 1.63 s ahead at a sampling frequency of 9.19 Hz). This concludes that a neuronal activation can be concluded in about 0.1 s with fNIRS using prediction, which enables an almost real-time practice if combined with EEG.

References

Jul 1, 1994·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·T Ernst, J Hennig
May 1, 1993·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·T KatoT Ozaki
Feb 17, 2001·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·E Yacoub, X Hu
Dec 18, 2001·NMR in Biomedicine·E YacoubX Hu
Apr 26, 2006·NeuroImage·Yashar Behzadi, Thomas T Liu
Feb 5, 2008·IEEE Transactions on Neural Networks·K R MüllerB Schölkopf
Oct 14, 2008·NeuroImage·Jong Chul YeJaeduck Jang
Jun 29, 2010·Seminars in Fetal & Neonatal Medicine·Adelina Pellicer, María del Carmen Bravo
Nov 19, 2010·PloS One·Xu CuiAllan L Reiss
Oct 11, 2011·Communications of the ACM·Dennis J McFarland, Jonathan R Wolpaw
Mar 20, 2012·NeuroImage·Xiaoping Hu, Essa Yacoub
Mar 23, 2012·Sensors·Luis Fernando Nicolas-Alonso, Jaime Gomez-Gil
Apr 6, 2013·NeuroImage·Hellmuth Obrig
Oct 1, 2013·Reviews in the Neurosciences·Alexis Ortiz-Rosario, Hojjat Adeli
Nov 21, 2013·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Zuyao Y ShanDavid C Reutens
May 9, 2014·Frontiers in Human Neuroscience·M Jawad KhanKeum-Shik Hong
Feb 13, 2015·Frontiers in Human Neuroscience·Noman Naseer, Keum-Shik Hong
Mar 31, 2015·PloS One·Thibault GateauFrederic Dehais
Oct 28, 2015·Biomedical Optics Express·M Jawad Khan, Keum-Shik Hong
Oct 5, 2016·Biomedical Optics Express·Hoang-Dung Nguyen, Keum-Shik Hong
Oct 28, 2016·PloS One·Hoang-Dung NguyenYong-Il Shin
Jan 20, 2017·Biomedical Optics Express·Amad Zafar, Keum-Shik Hong
Feb 16, 2017·Proceedings of the National Academy of Sciences of the United States of America·Hama WatanabeGentaro Taga
Mar 7, 2017·Frontiers in Neurorobotics·Muhammad Jawad Khan, Keum-Shik Hong
Jul 3, 2017·Behavioural Brain Research·Keum-Shik HongYong-Il Shin
Oct 3, 2017·Frontiers in Human Neuroscience·Rihui LiYingchun Zhang
Nov 23, 2017·Frontiers in Neurorobotics·Usman GhafoorKeum-Shik Hong

❮ Previous
Next ❯

Methods Mentioned

BETA
ISS

Software Mentioned

ISS Imagent
Matlab TM
ISS
- Boxy
RLS
KRLS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.