Reduction of postoperative spinal infections based on an etiologic protocol

Clinical Orthopaedics and Related Research
Anastasios G ChristodoulouJohn Pournaras

Abstract

Acute postoperative spinal infections are serious complications. We saw a sudden increase in the infection rate in our unit during a 6-month period. This led us to construct an assessment protocol combining risk factors into a mnemonic we named the "Nine Ps Protocol" (patient-related factors, personnel, place, preoperative length of stay, procedure, prosthetics, prophylaxis, packed red blood cells, and pus cultures). We reviewed 102 consecutive patients having spine surgery in three sequential 6 month periods: Group A included 34 patients before the outbreak of infection and Group B included 26 patients during the outbreak of infection. We prospectively applied the protocol in 26 patients (Group C) after the outbreak. After the implementation of the protocol the infection rate dropped from 16.7% (Group B) to 3.6% (Group C). Increased risk factors for postoperative infection included advanced age, posterior instrumented fusion, high allogenic blood transfusion rates, and suboptimal sheet and dressing changing conditions. We propose the Nine Ps Protocol as a useful clinical tool for the etiologic assessment and prevention of spinal infections. Prognostic study, Level II (Lesser quality prospective study [eg, patients enrolled at ...Continue Reading

References

Aug 1, 1995·Journal of Spinal Disorders·D M AbbeyR D Scalley
Apr 1, 1997·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J W PerryK Maeder
Jun 1, 1997·Journal of Neurosurgery·A D LeviV K Sonntag
Dec 16, 1998·Southern Medical Journal·S D HodgesN G Kurzynske
Oct 29, 2000·Journal of Spinal Disorders·M A WeinsteinF P Cammisa
Apr 10, 2002·Transfusion Medicine Reviews·Eleftherios C Vamvakas
Mar 26, 2003·Journal of Neurosurgery·Margaret A OlsenVictoria J Fraser
Jun 5, 2003·Clinical Orthopaedics and Related Research·Konstantinos SoultanisPanayotis N Soucacos
Sep 7, 2004·Neurosurgical Focus·John M BeinerAlexander R Vaccaro

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Citations

Nov 26, 2009·Journal of Neurosurgery. Spine·John E O'TooleRichard G Fessler
Aug 15, 2015·BioMed Research International·Jung-Tung LiuYung-Hsiang Chen
Mar 8, 2016·Asian Spine Journal·Abhijit Yuvaraj Pawar, Samar Kumar Biswas
Jun 6, 2008·Current Opinion in Rheumatology·Irene S KourbetiDimitrios T Boumpas
Dec 18, 2013·Surgical Neurology International·Manish K KasliwalVincent C Traynelis
Nov 4, 2017·Advances in Orthopedics·Vincenzo De LunaRoberto Caterini
Jan 10, 2020·Clinical Spine Surgery : a Spine Publication·Adan OmarAddisu Mesfin
Oct 21, 2017·Spine Deformity·Ravi S BainsCary Idler
Apr 11, 2017·Surgical Infections·Alyssa G BloodKatherine Halverson-Carpenter
Nov 1, 2017·Spine Deformity·Ravi S BainsCary Idler
Sep 15, 2011·The Journal of Bone and Joint Surgery. American Volume·Stelios KoutsoumbelisAndrew A Sama

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