Reduction of somatosensory functional connectivity by transcranial alternating current stimulation at endogenous mu-frequency.

NeuroImage
Christopher GundlachBernhard Sehm

Abstract

Alpha, the most prominent human brain rhythm, might reflect a mechanism of functional inhibition for gating neural processing. This concept has been derived predominantly from local measures of inhibition, while large-scale network mechanisms to guide information flow are largely unknown. Here, we investigated functional connectivity changes on a whole-brain level by concurrent transcranial alternating current stimulation (tACS) and resting-state functional MRI in humans. We specifically focused on somatosensory alpha-band oscillations by adjusting the tACS frequency to each individual´s somatosensory (mu-) alpha peak frequency (mu-tACS). Potential differences of Eigenvector Centrality of primary somatosensory cortex (S1) as well as on a whole brain level between mu-tACS and sham were analyzed. Our results demonstrate that mu-tACS induces a locally-specific decrease in whole-brain functional connectivity of left S1. An additional exploratory analysis revealed that this effect primarily depends on a decrease in functional connectivity between S1 and a network of regions that are crucially involved in somatosensory processing. Furthermore, the decrease in functional centrality was specific to mu-tACS and was not observed when tAC...Continue Reading

References

Jan 1, 1977·Electroencephalography and Clinical Neurophysiology·G PfurtschellerS Schuy
Jun 1, 1997·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·G PfurtschellerG Edlinger
Nov 27, 1999·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·G Pfurtscheller, F H Lopes da Silva
Mar 29, 2001·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·R Oostenveld, P Praamstra
Oct 27, 2001·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·G LohmannD Y von Cramon
Jun 26, 2004·Science·György Buzsáki, Andreas Draguhn
Jul 3, 2004·Science·H Henrik EhrssonRichard E Passingham
Jul 23, 2004·Brain Research. Cognitive Brain Research·Tolgay ErgenogluYagiz Uresin
Nov 13, 2004·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Klaus Linkenkaer-HansenJ Matias Palva
Jul 14, 2005·Journal of Anatomy·Christian Grefkes, Gereon R Fink
Jan 24, 2006·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Prateek C GandigaLeonardo G Cohen
Apr 26, 2006·NeuroImage·K J FristonR N Henson
Aug 5, 2006·Brain Research Reviews·Wolfgang KlimeschSimon Hanslmayr
Feb 20, 2007·Trends in Neurosciences·Satu Palva, J Matias Palva
Mar 6, 2007·NeuroImage·J C de MunckF H Lopes da Silva
Apr 26, 2007·PLoS Biology·Joachim GrossMarkus Ploner
Jun 23, 2007·Journal of Cognitive Neuroscience·Chris RordenLeonardo Bonilha
Feb 22, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Hanneke van DijkOle Jensen
Feb 28, 2008·Journal of Magnetic Resonance Imaging : JMRI·Clifford R JackMichael W Weiner
Dec 23, 2008·PloS One·Daria OsipovaOle Jensen
Feb 10, 2009·Journal of Cognitive Neuroscience·Ruth SchubertGabriel Curio
Nov 10, 2009·Behavior Research Methods·Franz FaulAlbert-Georg Lang
May 1, 2010·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Steen MoellerKâmil Uğurbil
Oct 15, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Stephanie R JonesChristopher I Moore
Nov 12, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Davide ReatoLucas C Parra
Apr 8, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Saskia HaegensOle Jensen
Jul 29, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Robert BeckerPetra Ritter
Aug 26, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Matteo FeurraSimone Rossi
Sep 13, 2011·NeuroImage·Catherine J StoodleyJeremy D Schmahmann
Oct 5, 2011·Cerebral Cortex·Xi-Nian ZuoMichael P Milham
Nov 16, 2011·Proceedings of the National Academy of Sciences of the United States of America·Saskia HaegensOle Jensen
Jul 28, 2012·NeuroImage·T NeulingC S Herrmann
Sep 4, 2012·Brain Connectivity·René ScheeringaMarcel C M Bastiaansen

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Citations

Jun 27, 2021·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Varg T KönigsmarkReshanne R Reeder
Jul 27, 2021·Frontiers in Human Neuroscience·Mária Orendáčová, Eugen Kvašňák

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