Reduction of spiral ganglion neurons in the aging canine with hearing loss

Zentralblatt für Veterinärmedizin. Reihe A
K KnowlesJ Hewett

Abstract

The middle and inner ears of 16 dogs, from 1.5 to 17 years of age, with differing degrees of suspected hearing loss were examined. Auditory function was assessed subjectively, and electrophysiologically by recording brainstem auditory-evoked responses (BAER) to click stimuli. Ossicular chains and stapediovestibular articulations were evaluated macroscopically and by light microscopy for evidence of bony ankylosis; no abnormalities were found. A determination of spiral ganglion packing density revealed a loss of spiral ganglion cells in all areas of the cochlea in dogs of the deaf group and in the upper and lower basal region of dogs from the hearing impaired group. The largest losses of spiral ganglion cells in the deaf group were located in the upper and lower basal region. The deaf group's density was reduced to 44% (upper basal) 15% (lower basal) of the normal hearing group. The largest spiral ganglion cell loss for dogs in the hearing impaired group occurred in the lower basal region where the density was reduced to 40% of the normal hearing group. These morphological findings in the aging canine are consistent with a peripheral nerve hearing loss.

References

Dec 1, 1979·The Journal of Comparative Neurology·E M Keithley, M L Feldman
Mar 1, 1976·The Annals of Otology, Rhinology, and Laryngology·F Suga, J R Lindsay
Dec 1, 1974·Experimental and Molecular Pathology·D S PackardR A Menzies
Apr 1, 1972·The Annals of Otology, Rhinology, and Laryngology·L G Johnsson, J E Hawkins
Dec 1, 1982·Hearing Research·E M Keithley, M L Feldman
Feb 1, 1964·The Laryngoscope·I KIRIKAET SHITARA
Oct 1, 1964·Archives of Otolaryngology·H F SCHUKNECHT
Jun 1, 1965·The Laryngoscope·J SATALOFFH MENDUKE
Aug 1, 1965·Archives of Otolaryngology·C C HANSEN, E RESKE-NIELSEN
Jan 1, 1952·Acta Oto-laryngologica·A SAXEN

❮ Previous
Next ❯

Citations

Jan 1, 1996·The British Veterinary Journal·G M Strain
Jun 20, 2008·Journal of Veterinary Internal Medicine·G Ter HaarG F Smoorenburg
Aug 4, 2009·Journal of Veterinary Internal Medicine·G Ter HaarG F Smoorenburg
Jul 18, 2006·Hearing Research·Tima Le, Elizabeth M Keithley
Mar 10, 1998·The Journal of Veterinary Medical Science·A ShimadaT Umemura
Feb 12, 1998·The Veterinary Clinics of North America. Small Animal Practice·R S Bagley
Oct 1, 2016·The Veterinary Journal·G M StrainC L McMillan
Jul 9, 2010·The Journal of Primary Prevention·Bruce G Simons-Morton, Tilda Farhat
Dec 29, 2005·American Journal of Veterinary Research·Wayne J Wilson, Paul C Mills
Dec 29, 2019·Scientific Reports·Iris SmitEnikő Kubinyi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Auditory Perception

Auditory perception is the ability to receive and interpret information attained by the ears. Here is the latest research on factors and underlying mechanisms that influence auditory perception.

Related Papers

Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine
C SalvadoriC Cantile
Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
Derek D Nestor, Diana S Rosenstein
Journal of the American Veterinary Medical Association
Kenneth R HarkinDavid S Biller
The Veterinary Record
M K Wilkes, A C Palmer
© 2022 Meta ULC. All rights reserved