Reemergence of yellow fever in Ethiopia after 50 years, 2013: epidemiological and entomological investigations

BMC Infectious Diseases
Abrham LilayDebritu Mengesha

Abstract

Yellow Fever (YF) is a viral hemorrhagic disease transmitted by aedes mosquito species. Approximately, 200,000 cases and 30,000 deaths occur worldwide every year. In Ethiopia, the last outbreak was reported in 1966 with 2200 cases and 450 deaths. A number of cases with deaths from unknown febrile illness reported from South Ari district starting from November 2012. This investigation was conducted to identify the causative agent, source of the outbreak and recommend appropriate interventions. Medical records were reviewed and Patients and clinicians involved in managing the case were interviewed. Descriptive data analysis was done by time, person and place. Serum samples were collected for serological analysis it was done using Enzyme-linked Immunosorbent Assay for initial screening and confirmatory tests were done using Plaque Reduction and Neutralization Test. Breteau and container indices were used for the entomological investigation to determine the risk of epidemic. A total of 141 Suspected YF cases with 43 deaths (CFR = 30.5%) were reported from November 2012 to October 2013 from South Omo Zone. All age groups were affected (mean 27.5, Range 1-75 Years). Of the total cases, 85.1% cases had jaundice and 56.7% cases had fev...Continue Reading

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Citations

Apr 10, 2018·PLoS Neglected Tropical Diseases·Mengistu LegesseGirmay Medhin
Dec 4, 2019·Vector Borne and Zoonotic Diseases·Monica A McArthurAlan D T Barrett
Aug 24, 2018·Genes·Raphaëlle KlittingXavier de Lamballerie
Jul 6, 2019·Scientific Reports·Nicholas J BarrowsMariano A Garcia-Blanco
Jun 13, 2018·Genes·Raphaëlle KlittingXavier de Lamballerie
Sep 5, 2020·Risk Management and Healthcare Policy·Adugna EndaleMengistu Legesse
Sep 4, 2020·PLoS Neglected Tropical Diseases·Adugna EndaleMengistu Legesse
Dec 30, 2020·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Getachew FeredeBelay Tessema

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Methods Mentioned

BETA
ELISA
PCR

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Excel Sheet
Geographic Information System ( GIS )

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