PMID: 7544193Apr 1, 1995Paper

Reentry: insights from theoretical simulations in a fixed pathway

Journal of Cardiovascular Electrophysiology
Y Rudy

Abstract

This review article summarizes theoretical insights into the principles and mechanisms associated with reentrant activity in cardiac tissue. A mathematical ring model is used in computer simulations to investigate, at the cellular level, mechanistic aspects of initiation, perpetuation, and termination of reentry. Taking advantage of the ability to compute membrane processes in this model, we relate dynamic properties of the reentrant action potential (e.g., beat-to-beat alternans) to the underlying kinetics of membrane ionic channels. Effects on reentry of inhomogeneities in refractoriness, excitability, cellular coupling at gap junctions, and fiber cross-section are also studied.

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Citations

Jul 10, 2007·Annals of Biomedical Engineering·Beatriz TrénorJosé Miguel Alonso
Jun 18, 2010·Progress in Biophysics and Molecular Biology·R H ClaytonH Zhang
Oct 3, 2003·Journal of Cardiovascular Electrophysiology·Chad R Johnson, Roger C Barr
Oct 4, 2006·Journal of Electrocardiology·Leslie Tung, Yibing Zhang
Jun 5, 2003·Chaos·David J. Christini, Leon Glass
Jun 5, 2003·Chaos·Sitabhra SinhaDavid J. Christini
Jan 27, 2017·Proceedings of the National Academy of Sciences of the United States of America·Vladimir ZykovEberhard Bodenschatz
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Jun 1, 1996·Physical Review. E, Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics·T Nomura, L Glass
Feb 28, 2002·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Leon GlassStanley Nattel
Feb 14, 2006·Circulation Research·Weining Bian, Leslie Tung
Nov 8, 2006·Circulation·Zhan Yang LimLeslie Tung
Sep 23, 2006·Journal of Cardiovascular Electrophysiology·Israel A ByrdAndrew E Pollard
Apr 3, 2012·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Qin LouYan Liu
Dec 6, 2007·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Christian W Zemlin, Arkady M Pertsov
Dec 25, 2003·American Journal of Physiology. Heart and Circulatory Physiology·Xianming Lin, Richard D Veenstra
Nov 14, 2018·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·V S Zykov
Jan 7, 2003·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Sitabhra Sinha, David J Christini
Oct 13, 2007·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Wei ChenAlain Vinet
Jan 14, 2021·Arrhythmia & Electrophysiology Review·Irum KotadiaMatthew Wright

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