Reevaluation of polychlorinated biphenyl concentrations in milk and body fat of lactating cows

Journal of Dairy Science
L B WillettG F Fries

Abstract

Polychlorinated biphenyls occur as mixtures of congeners, each of which may be absorbed, excreted, or metabolized differently. Quantification of polychlorinated biphenyls by packed-column GLC has been difficult. Many quantification techniques, generally based on quantification of a selected group of the congeners present, have been used by researchers. Results of these studies have not provided a consistent basis to determine the relationship between the amounts of polychlorinated biphenyls consumed and residual polychlorinated biphenyls in milk and animal tissues. In the present study, we hypothesized that if a standardized quantification procedure was applied, consistent dose:residue predictions could be made. Weighted percentage of each peak in the polychlorinated biphenyl mixture procedures was used as a standard method to quantify polychlorinated biphenyls in milk fat from published and unpublished studies where lactating cows were fed between 3.5 and 1000 mg/d (Aroclor 1254) for greater than or equal to 15 d. When steady state occurred by 60 d of dosing, the relationship between concentration in milk fat (microgram/g) and daily dose as mg and as mg/kg BW were described by the equations: [polychlorinated biphenyls, microgr...Continue Reading

References

Jan 1, 1975·Residue Reviews·L B Willett, J F Hess
Jul 1, 1987·Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology·L B WillettD R Redman
Jul 1, 1973·Journal of Chromatographic Science·R G Webb, A C McCall
Jan 1, 1973·Journal of Agricultural and Food Chemistry·G F FriesC H Gordon
Sep 1, 1983·Bulletin of Environmental Contamination and Toxicology·L A PetersonH A Nelson
Jan 1, 1984·Journal of Dairy Science·T W PerryF R Robinson
Sep 1, 1984·Bulletin of Environmental Contamination and Toxicology·L F de AlencastroJ Tarradellas
Nov 1, 1981·Journal of Dairy Science·T W PerryF R Robinson
Jan 1, 1982·Journal of Dairy Science·L B Willett, T T Liu

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Citations

Jun 1, 1993·Journal of Dairy Science·L B WillettM M Kurz

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