Reference centiles for the gross motor function measure and identification of therapeutic effects in children with cerebral palsy

Journal of Evaluation in Clinical Practice
I DuranE Schoenau

Abstract

Children with cerebral palsy (CP) can show an increase in gross motor function until the age of 9 to 10 years under the standard of care. Additionally, the motor development can have large individual fluctuations. Therefore, in clinical setting, it is not trivial to estimate the effect of an additional therapeutic intervention at this age interval. The study aim was to develop a method which allows quantification of the gross motor function changes over 6 months of the individual child with CP. The present study was a single center retrospective analysis. Data were collected in children with CP who participated in a rehabilitation program between 2006 and 2016. The gross motor function of the children was measured with the Gross Motor Function Measurement (GMFM-66). Reference centiles for the GMFM-66 were created with data before starting the rehabilitation program. The variability of the evolution of the GMFM-66 was assessed with data at the start and the end of a 6-month observational phase of standard of care. In total, the GMFM-66 data of 919 children before starting the rehabilitation program were available (age 6.49 ± 2.49 years, GMFCS-level I-V). For 515 study participants (6.76 ± 2.30 years, GMFCS-level I-V), data were ...Continue Reading

References

Jul 1, 1992·Statistics in Medicine·T J Cole, P J Green
Dec 1, 1989·Controlled Clinical Trials·R JaeschkeG H Guyatt
Jun 1, 1989·Developmental Medicine and Child Neurology·D J RussellS Jarvis
Apr 1, 1997·Developmental Medicine and Child Neurology·R PalisanoB Galuppi
Sep 18, 2002·JAMA : the Journal of the American Medical Association·Peter L RosenbaumBarbara E Galuppi
Apr 24, 2009·Brain & Development·Ingeborg Krägeloh-Mann, Christine Cans
Apr 25, 2009·Developmental Medicine and Child Neurology·Steven E HannaDianne J Russell
Mar 19, 2011·BMC Bioinformatics·Xavier RobinMarkus Müller
Jan 30, 2013·Developmental Medicine and Child Neurology·Dirk-Wouter SmitsUNKNOWN PERRIN Plus Study Group
Aug 21, 2015·Archives of Physical Medicine and Rehabilitation·Pierre MaroisLaurent Ballaz

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Citations

May 20, 2020·Physical & Occupational Therapy in Pediatrics·Samuel R PierceLaura A Prosser
Feb 10, 2020·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Kristina RuthardEckhard Schönau

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