Reference chart for knee flexion following total knee arthroplasty: a novel tool for monitoring postoperative recovery.

BMC Musculoskeletal Disorders
Andrew J KittelsonJennifer Stevens-Lapsley

Abstract

Clinicians and patients lack an evidence-based framework by which to judge individual-level recovery following total knee arthroplasty (TKA) surgery, thus impeding personalized treatment approaches for this elective surgery. Our study aimed to develop and validate a reference chart for monitoring recovery of knee flexion following TKA surgery. Retrospective analysis of data collected in routine rehabilitation practice for patients following TKA surgery. Reference charts were constructed using Generalized Additive Models for Location Scale and Shape. Various models were compared using the Schwarz Bayesian Criterion, Mean Squared Error in 5-fold cross validation, and centile coverage (i.e. the percent of observed data represented below specified centiles). The performance of the reference chart was then validated against a test set of patients with later surgical dates, by examining the centile coverage and average bias (i.e. difference between observed and predicted values) in the test dataset. A total of 1173 observations from 327 patients were used to develop a reference chart for knee flexion over the first 120 days following TKA. The best fitting model utilized a non-linear time trend, with smoothing splines for median and v...Continue Reading

References

Nov 20, 2002·Clinical Orthopaedics and Related Research·Jennifer M WeissKenneth B Mathis
Sep 8, 2004·Statistics in Medicine·Robert A Rigby, D Mikis Stasinopoulos
Mar 19, 2005·BMJ : British Medical Journal·Paul GlasziouDavid Mant
Sep 14, 2006·JAMA : the Journal of the American Medical Association·Helena C KraemerDavid J Kupfer
Dec 13, 2006·BMC Musculoskeletal Disorders·Deborah M KennedyJeffrey D Gollish
Nov 8, 2007·Physical Therapy·Deborah M KennedyJeffrey D Gollish
Feb 11, 2009·Australian Health Review : a Publication of the Australian Hospital Association·Justine M NaylorIan A Harris
Mar 16, 2011·International Orthopaedics·Steven M KurtzChristoph Röder
Feb 11, 2014·American Journal of Physical Medicine & Rehabilitation·Michael J BadeJennifer E Stevens-Lapsley
Apr 18, 2015·Bulletin of the World Health Organization·Daniel J HayesDianne J Terlouw
May 1, 2015·Nature·Nicholas J Schork
Oct 15, 2019·Physical Therapy·Andrew J KittelsonNico L U van Meeteren

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Software Mentioned

Research Electronic Data Capture ( REDCap )
GAMLSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Rural Medicine : JRM
Hirotaka MutsuzakiYasuyoshi Wadano
Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA
Sérgio Rocha PiedadePhilippe Neyret
Clinical Orthopaedics and Related Research
Peter G SultanHarry Rubash
© 2021 Meta ULC. All rights reserved