Reference ranges for and determinants of right ventricular area in healthy adults by two-dimensional echocardiography

Respiration; International Review of Thoracic Diseases
Ekkehard GrünigEduardo Bossone

Abstract

The right ventricular (RV) area is important for diagnosis and follow-up in patients with various diseases, such as in pulmonary hypertension. The aim of this study was to define the reference ranges of the end-diastolic RV area in healthy adults and to assess the determining factors. In the first part of the study 860 healthy subjects (37.6% female; mean age 28 ± 5.84; 395 endurance athletes, 255 strength athletes and 210 non-athletes) were prospectively assessed. In the second part we performed a pooled analysis of studies published between 1979 and 2014 describing the RV area in healthy subjects (n = 5,248). Statistical analysis included the calculation of reference ranges and the analysis of determining factors. Mean end-diastolic RV areas in 860 healthy subjects were significantly larger in endurance athletes (25.1 ± 2.0 cm(2)) compared with strength athletes (22.9 ± 1.7 cm(2)) and non-athletes (16.7 ± 2.0 cm(2), p < 0.001). In the synopsis of both data sets, mean end-diastolic RV area was significantly larger in European/American males (17 cm(2)) compared with females (14 cm(2), p < 0.001) and in Asian males (16 cm(2)) compared with females (13 cm(2), p < 0.001). The area increased with body surface area and older age. Th...Continue Reading

Citations

Oct 8, 2016·The International Journal of Cardiovascular Imaging·Alberto M MarraEduardo Bossone
Sep 15, 2018·Journal of Veterinary Internal Medicine·Tommaso VezzosiRosalba Tognetti
Dec 2, 2015·European Respiratory Review : an Official Journal of the European Respiratory Society·Ekkehard Grünig, Andrew J Peacock
Oct 9, 2015·Current Opinion in Cardiology·Eduardo BossoneEkkehard Grünig
Jun 20, 2019·Internal and Emergency Medicine·Alberto Maria MarraAntonio Cittadini

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