Reference Ranges for the Non-High-Density Lipoprotein Cholesterol Levels in Japanese Children and Adolescents

Journal of Atherosclerosis and Thrombosis
Yuriko AbeMitsunori Murata

Abstract

The aim of this study was to identify the age and sex-specific reference ranges for the non-high-density lipoprotein cholesterol (non-HDLC) levels in Japanese children. The subjects included 441,431 schoolchildren (207,015 boys, 234,416 girls) 9-16 years of age who participated in a screening and care program for lifestyle-related diseases from 2006 to 2011. The serum total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C) and triglyceride (TG) levels were measured, and the non-HDL-C levels were calculated. The serum lipid levels were analyzed according to age and sex. The overall mean non-HDL-C level was 105.7±24.0 mg/dL, with a sex difference: boys= 103.0±24.0 mg/dL and girls=108.2±23.8 mg/dL. In boys, the median non-HDL-C level decreased gradually from 104 mg/dL in the 9-year-old age group to 96 mg/dL in the 15-year-old age group. The 75th percentile level was approximately 120 mg/dL in the 9- to 11-year-old groups and decreased at approximately 113 mg/dL in the 12- to 15-year-old groups, whereas the 95th percentile level was approximately 150 mg/dL in the 9- to 11-year-old groups and decreased at approximately 140 mg/dL in the 13- to 15-year-old groups. In girls, the median non-HDL-C level remained unchanged at...Continue Reading

References

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Citations

Jun 13, 2015·Journal of Atherosclerosis and Thrombosis·Kazushige Dobashi
Nov 12, 2017·Indian Journal of Pediatrics·Toshihide KuboKenji Urayama
Aug 24, 2018·Journal of Atherosclerosis and Thrombosis·Makoto KinoshitaUNKNOWN Committee for Epidemiology and Clinical Management of Atherosclerosis
Dec 16, 2016·Journal of Pediatric Endocrinology & Metabolism : JPEM·Toshihide KuboKenji Urayama
Sep 29, 2015·Journal of Atherosclerosis and Thrombosis·Emiko SaitoMitsuhiko Hara
Feb 23, 2021·Journal of Atherosclerosis and Thrombosis·Kazushige Dobashi
Oct 7, 2020·Pediatrics International : Official Journal of the Japan Pediatric Society·Ryousuke TonouchiIchiro Morioka
Jul 17, 2021·Journal of Sports Science & Medicine·Tetsuhiro Kidokoro, Kanako Edamoto

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