PMID: 2097078Jan 1, 1990Paper

Reference values for circadian rhythms of 98 variables in clinically healthy men in the fifth decade of life

Chronobiology International
E L KanabrockiH Ferlin

Abstract

Nine clinically healthy men, 41-47 yr of age, served as subjects in a 24-hr study conducted at the Edward Hines Jr Veterans Administration Hospital in the Chicago area in May 1988. Physiologic measurements, and blood and urine samples were collected at 3-hr intervals over a single 24-hr period beginning at 1900. The number of variables measured or calculated (total = 98) included: 6 vital signs (oral temperature, pulse, blood- and intraocular pressures); 16 in whole blood (counts and differentials); 50 in serum (SMAC-24, lipids, hormones, electrophoresis of LDH and proteins); and 26 in urine (solids, proteins, creatinine, catecholamines, melatonin, cortisol, electrolytes and metals). Data were analyzed for time effect by analysis of variance (ANOVA) and for circadian rhythm by single cosinor. Individual rhythm characteristics for each variable were summarized for the group by population mean cosinor. The vast majority of variables revealed statistically significant within-day changes in values as validated by one-way ANOVA. All vital signs (except for intraocular pressures) and all serum hormones displayed a prominent circadian rhythm for the group, as did most variables in whole blood, while only about half of the variables in...Continue Reading

References

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Citations

Sep 1, 1983·Biulleten' eksperimental'noĭ biologii i meditsiny·T P RiabykhA P Suslov
Jul 3, 2002·Aging Clinical and Experimental Research·Rosita TrottiGianvico Melzi d'Eril
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Jan 1, 2007·Biological Rhythm Research·Roberto RefinettiFranz Halberg
Nov 21, 2012·Journal of Clinical Gastroenterology·Constance E Ruhl, James E Everhart
Feb 19, 2009·The Journal of Clinical Endocrinology and Metabolism·Miguel DebonoRichard J Ross
Jun 1, 1993·Chronobiology International·A Rivera-CollA Díez-Noguera
Mar 9, 2012·Scandinavian Journal of Clinical and Laboratory Investigation·Henriette P SennelsJan Fahrenkrug
Oct 13, 2011·Scandinavian Journal of Clinical and Laboratory Investigation·Henriette P SennelsJan Fahrenkrug
Sep 18, 2015·Scandinavian Journal of Clinical and Laboratory Investigation·Henriette P SennelsJan Fahrenkrug
Jun 3, 2000·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·S J LugowskiJ Semple
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May 17, 2018·Scandinavian Journal of Clinical and Laboratory Investigation·Mustafa K Özçürümez, Rainer Haeckel
May 19, 2016·Journal of Strength and Conditioning Research·Achraf AmmarNizar Souissi
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Mar 22, 2000·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·E L KanabrockiL E Scheving
Apr 19, 2002·Chronobiology International·Rune SmaalandJenny Foss Abrahamsen
Sep 7, 2007·Advanced Drug Delivery Reviews·Erhard Haus

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