Reference values for lung function screening in 10- to 81-year-old, healthy, never-smoking residents of Southeast China

Medicine
Chunlin GaoZhongming Li

Abstract

No official spirometry reference values for Chinese are available.To establish new Chinese reference values and prediction equations for lung parameters in Chinese individuals of 10 to 81 years of age.Pulmonary functions were measured according to the American Thoracic Society criteria in 1457 subjects from the Zhejiang coastal province (China). The subjects were 10 to 81 years of age, nonsmokers, and without chronic or acute diseases. Multiple stepwise linear regression analysis was performed for each parameter against age, height, weight, and body mass index (BMI; kg/m) for males and females separately.Most lung function variables were nonlinear with age and showed a plateau in younger adults, with a decline after 31 to 35 years. All spirometric data of men were higher than those of women except breathing frequency and forced expiratory volume in 1 second (FEV1)/forced vital capacity (FVC). All measured lung function parameters were strongly correlated to age, height, weight, and BMI. The highest correlation being to height in both men and women except for tidal volume and expiratory reserve volume among women. Based on previous studies, Caucasians men from the USA and Switzerland had higher FVC and FEV1 than in the present s...Continue Reading

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