PMID: 3750392Sep 1, 1986Paper

Reference values for serum folate, erythrocyte folate and serum cobalamin in Nigerian adolescents

Tropical and Geographical Medicine
B O OsifoJ O Bolodeoku

Abstract

Concentrations of serum folate, red cell folate and serum cobalamin were studied among 240 normal healthy Nigerian adolescents aged 12-17 years. Serum folate level was generally low with a mean of 2.8 nmol/l while red cell folate level was not low with a mean of 369 nmol/l. Mean serum cobalamin was 615 pmol/l. A negative significant correlation was observed between serum folate and red cell folate among the adolescents (r = 0.24). Another significant correlation was observed among the 14 year olds between red cell folate and serum cobalamin (r = 0.404). The folate parameters were significantly lower in the adolescents with HbAS genotype with mean serum folate of 2.2 nmol/l and red cell folate of 326 nmol/l but these differences were more marked among the girls. All the girls in the study had significantly higher serum cobalamin than the boys (p less than 0.001) but the advantage of this is not clear. These results suggest that serum cobalamin may be under some hormonal influences and the high values indicate that cobalamin may be involved in other metabolic functions from the puberty period.

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Journal of Pediatrics
L M OginniM W Davie
East African Medical Journal
A O OlukogaM A Adedoyin
International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics
O O AbuduO A Oluboyede
© 2021 Meta ULC. All rights reserved