Referral for Ophthalmology Evaluation and Visual Sequelae in Children With Primary Brain Tumors

JAMA Network Open
Yin LiuTimothy W Winter

Abstract

Visual impairment in children with brain tumors has received limited attention, as most pediatric neuro-oncology clinical trials neither require ophthalmologic evaluation on enrollment nor monitor effects of treatment on visual function during and after treatment. To investigate ophthalmology referral patterns for children with primary brain tumors, the prevalence of visual sequelae, and the association between tumor characteristics and vision-related diagnoses. This retrospective cohort study included 141 children with primary brain tumors treated at Loma Linda University Children's Hospital and Eye Institute, a university-based tertiary referral center, between January 2013 and September 2017. Data analysis was completed in March 2019. Comprehensive ophthalmologic evaluation for children with primary brain tumors. Percentage of patients with ophthalmology evaluation, prevalence of abnormal ophthalmic findings, and their association with tumor characteristics. A total of 141 children (73 [52%] male; median [range] age, 7 [0-18] years) with primary brain tumors were enrolled in this study. Seventy-three patients (41 [52%] male; median [range] age, 8 [0-17] years) never had formal ophthalmologic evaluation. Sixty-eight patients ...Continue Reading

References

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Jan 22, 2019·Pediatric Neurology·Nisha GadgilVeeral Shah

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Citations

Oct 2, 2020·PloS One·Myrthe A NuijtsAntoinette Y N Schouten-van Meeteren
Jun 1, 2021·Case Reports in Ophthalmological Medicine·Megha KotechaPrashant Punia
Sep 1, 2021·Journal of Neuro-oncology·Jason H PeragalloValérie Biousse

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BETA
surgical resection

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SPSS

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