Refining a health-related quality of life assessment strategy for solid organ transplant patients

Clinical Transplantation
Irene D FeurerC Wright Pinson

Abstract

The psychometric properties of generic health-related quality of life (HRQOL) assessment instruments were evaluated to identify a reliable, valid, and non-redundant battery to measure longitudinal outcomes in organ transplant patients. Objective functional performance and subjective HRQOL were assessed in 371 solid organ (liver, heart, kidney, lung) transplant patients using the Karnofsky scale, the SF-36 Health Survey (SF-36), and Psychosocial Adjustment to Illness Scale (PAIS). The surveys' internal-consistency reliability, criterion-related validity, and redundancy were tested. The SF-36 mental (MCS) and physical components (PCS), and PAIS summary scales were internally consistent (all alpha > or = 0.83). Four out of seven PAIS scales (vocational, domestic, sexual, social) were collectively associated with the PCS (R = 0.65, P < 0.001), as was functional performance (r = 0.52, P < 0.001). Three PAIS scales (family, social, psychological distress) were associated with the MCS (R = 0.72, P < 0.001). Only the PAIS healthcare orientation (satisfaction) scale was not associated with the SF-36((R)). The relationship between functional performance and the PCS is stronger (r = 0.52, P < 0.001) than with the MCS (r = 0.25, P < 0.001)...Continue Reading

References

Oct 1, 1983·Journal of the American Podiatry Association·R D Phillips, R L Phillips
Oct 1, 1994·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·R D HaysW B Carter
Apr 5, 2000·PharmacoEconomics·S J CoonsR D Hays
Sep 11, 2001·Journal of the American College of Surgeons·V Velanovich

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Citations

Aug 13, 2008·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·R T RussellC Wright Pinson
May 17, 2008·Clinical Transplantation·Zeeshan ButtDavid Cella
Nov 3, 2007·Liver International : Official Journal of the International Association for the Study of the Liver·Daniela R M GotardoMarcel C C Machado
Jul 11, 2006·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·J S SagerJ D Christie
Feb 26, 2013·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·J P SingerH Chen
Dec 19, 2019·World Journal of Transplantation·Natasha H DolginAdel Bozorgzadeh

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