PMID: 3745776Jul 1, 1986Paper

Reflex excitation and inhibition of the lower oesophageal sphincter induced by gastric distension in the cat

Journal of the Autonomic Nervous System
J P Niel

Abstract

Reflex responses of the lower oesophageal sphincter (l.o.s.) to distension of the stomach were studied by electromyographic and manometric techniques. Distension of the fundus and gastric antrum by inflation of a balloon elicited two types of reflex response of the l.o.s. Thus, whereas excitatory responses were recorded following slight distensions, larger distensions resulted in inhibitory responses. Splanchnic fibres and sympathetic fibres originating from the stellate ganglion, as well as vagal fibres served as the efferent pathways for the excitatory reflex response. The efferent pathways for the inhibitory response involved only vagal fibres.

References

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Feb 1, 1971·The Journal of Clinical Investigation·S Cohen, W Lipshutz
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