PMID: 3773326Jan 1, 1986

Reflex renal vasoconstriction on portal vein distension

The Japanese Journal of Physiology
S KoyamaT Takeuchi

Abstract

The present experiments were designed to study effects of neural control mechanisms on renal sympathetic nerve activity during acute portal vein distension in anesthetized dogs. Following the inflation of a balloon placed into the main portal vein of animals with the neuraxis intact (intact group), portal vein pressure at a site of the splanchnic regions increased significantly. Mean blood pressure (MBP) fell significantly and then renal vascular resistance (RVR) increased significantly in parallel with changes in portal venous pressure. In animals with sinoaortic denervation (SAD group), changes in portal venous pressure during the inflation of a balloon did not differ from the intact group. However, decreases in MBP in the SAD group were greater than that in the intact group, and sinoaortic denervation did not alter increases in RVR. In animals with both sinoaortic denervation and cervical vagotomy (vagotomy group), portal vein distension produced more profound hypotension, and significant increases in RVR occurred. This increase in RVR, however, was abolished by renal nerve denervation. The results of the present study indicate that increases in RVR during the portal vein distension, which is associated with systemic hypoten...Continue Reading

Citations

Jun 1, 1988·Journal of the Autonomic Nervous System·S KoyamaT Fujita
May 9, 2014·The American Journal of the Medical Sciences·Fadi RzouqMojtaba Olyaee
Sep 23, 2016·Surgical Neurology International·Michael D Wider
Sep 2, 2017·Journal of the American Heart Association·Marat FudimG Michael Felker
Aug 24, 2007·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Shereen M Hamza, Susan Kaufman

Related Concepts

Diastolic Blood Pressure
Denervation
Canis familiaris
Glomerular Filtration Rate
Kidney
Portal Vein Structure
Pressoreceptors
Reflex Action
Renal Blood Flow
Sympathetic Nervous System

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