Refractive lens exchange with intraocular lens implantation in hyperopic eyes of a patient with Angelman syndrome.

Journal of Cataract and Refractive Surgery
Rupal H Trivedi, M Edward Wilson

Abstract

We describe a patient with Angelman syndrome with severe developmental delay who was visually impaired by uncorrected high hyperopia and poor control of accommodation. Refractive lens exchange with intraocular lens implantation was performed in both eyes when the patient was 22 years of age. Satisfactory anatomical and functional outcomes were achieved and maintained during 3 years of follow-up. Refractive lens exchange can be useful in patients with severe neurobehavioral disorders in the presence of high refractive error and poor accommodative control. Neither author has a financial or proprietary interest in any material or method mentioned.

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Citations

Aug 17, 2014·Survey of Ophthalmology·Jorge L AlioDorota Romaniuk
Dec 25, 2010·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Amy L SheppardLeon N Davies
Jan 1, 2014·Eye and Vision·Jorge L AlióDorota Romaniuk

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Angelman syndrome is a neurogenetic imprinting disorder caused by loss of the maternally inherited UBE3A gene and is characterized by generalized epilepsy, limited expressive speech, sleep dysfunction, and movement disorders. Here is the latest research.