Regeneration of intact spleen in a heterotropic site in splenectomized mice

British Journal of Haematology
T F Warner, R G Krueger

Abstract

The regeneration of intact spleens implanted in the sacrospinal areas of splenectomized mice was studied by light microscopy. The weight of the implanted tissue was not fully regenerated 50 days after implantation. The pattern of embryonic development of the spleen was investigated and the histologic appearance of the implant 46 days after implantation resembled that of normal spleen. The appearance of primitive myelopoietic stem in cells in the early phases of regeneration makes this an attractive model in which to study the biologic effects of tumour viruses.

References

Sep 1, 1971·The Journal of Pathology·J F Kerr
Jul 17, 1970·Science·M Tavassoli, W H Crosby
Jul 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·D Zucker-FranklinP L'Esperance
Oct 1, 1959·The Journal of Pathology and Bacteriology·G R CAMERON, K S RHEE

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Citations

Jan 1, 1986·Virchows Archiv. A, Pathological Anatomy and Histopathology·M T MooreG G Jamieson
Jan 1, 1982·The Journal of Surgical Research·D D OakesA C Charters
Jun 1, 1981·Journal of Pediatric Surgery·D R CooneyJ E Fisher

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