Regeneration potential of pulp-dentin complex: Systematic review.

Journal of Conservative Dentistry : JCD
R Pramila, Ms Muthu

Abstract

The aim is to review and discuss the strategies available for the regeneration of tooth tissues based on principles of tissue engineering. Tissue engineering is a multidisciplinary approach that aims to regenerate functional tooth-tissue structure based on the interplay of three basic key elements: Stem cells, morphogens and scaffolds. A number of recent clinical case reports have revealed the possibilities that many teeth that traditionally would be treated byapexification may be treated by apexogenesis. Electronic and hand search of scientific papers were carried out on the Entrez Pubmed, and the Cochrane Central Register of Controlled Trials databases using specific keywords. Specific inclusion and exclusion criteria were predetermined. The search yielded 1619 papers; out of which 65 were identified as conforming to the predetermined inclusion criteria and the remaining 1554 were excluded. Out of 65 papers, 34 papers were excluded again as different key words led to the same publications. Only 31 papers were selected, out of which 27 full-text papers were found and 4 papers were included based on only the abstracts. These 31 papers formed the basis of this review. The data were extracted from the selected studies. The data w...Continue Reading

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Citations

Oct 12, 2014·Journal of Endodontics·Adam EckhardtIvan Mikšík
Dec 17, 2014·Journal of Endodontics·Mostafa EzEldeenReinhilde Jacobs
Aug 14, 2012·International Endodontic Journal·V C B LeituneS M W Samuel
Jun 2, 2017·The Open Dentistry Journal·Pollyana Rodrigues de Souza AraújoGerhilde Callou Sampaio
Jan 1, 2013·The Journal of Clinical Pediatric Dentistry·Sheila Daiane BarrosoKarine Taís Aguiar Tavano

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