Regenerative endodontic therapy of immature permanent molars with pulp necrosis: a cases series and a literature review.

European Archives of Paediatric Dentistry : Official Journal of the European Academy of Paediatric Dentistry
G N TzanetakisN Lygidakis

Abstract

To present the application and the outcome of the regenerative endodontic therapy (RET) in a series of symptomatic immature mandibular molars with pulp necrosis and apical periodontitis and to review the relevant literature for the documentation of the procedure as a potential treatment option. Three young male patients were referred with pain in the left mandibular region resulting from pulp necrosis and apical periodontitis of the first permanent molar. Regenerative endodontic approach was performed for the complete resolution of the lesions and the thickening of the apical root canal walls. The databases of Medline, Pubmed and Google Scholar were also searched for articles in which a regenerative approach has been undertaken for the endodontic management of immature permanent molars with pulp necrosis and apical periodontitis. Follow-up examinations showed that the teeth remained functional without any signs or symptoms. Final radiographic examination at 12, 18 and 36 months, respectively, revealed complete resolution of the lesions and complete apical closure in the two out of three cases. The search of the literature revealed the existence of only 25 clinical articles in which necrotic immature molars were treated by the r...Continue Reading

References

Jan 27, 2009·Journal of Endodontics·Ling-Huey ChuehChun-Pin Chiang
Mar 6, 2013·Journal of Endodontics·Kenneth M HargreavesFabricio B Teixeira
Jul 17, 2013·The Journal of Clinical Pediatric Dentistry·I S SönmezM Erkmen Almaz
Apr 29, 2014·Journal of Endodontics·Juliana Yuri NagataAdriana de Jesus Soares
Oct 11, 2014·Journal of Endodontics·Evangelos G KontakiotisAnastasia Agrafioti
Dec 3, 2014·Journal of Endodontics·Tugba BezginHayriye Sonmez
Mar 19, 2016·International Endodontic Journal·K M GallerP Lambrechts
Oct 12, 2016·Journal of Endodontics·Sarah BukhariBekir Karabucak
Jan 24, 2017·Journal of Endodontics·Edwin Ka Meng ChanBeatriz Ferraz Dos Santos
Aug 26, 2017·Case Reports in Dentistry·López CarmenYáñez-Vico Rosa
Oct 28, 2017·Case Reports in Dentistry·Said DhaimyAmal El Ouazzani
Dec 13, 2017·Journal of Endodontics·Jonathan Y LeeThomas A Beltran
Jan 18, 2018·European Archives of Paediatric Dentistry : Official Journal of the European Academy of Paediatric Dentistry·F MasmoudiF Maatouk
May 20, 2018·International Endodontic Journal·S G KimB Kahler
Nov 28, 2018·Journal of Endodontics·Mahmoud TorabinejadShahrokh Shabahang

❮ Previous
Next ❯

Citations

Oct 29, 2020·European Archives of Paediatric Dentistry : Official Journal of the European Academy of Paediatric Dentistry·M YoshpeM Ashkenazi
Jun 11, 2021·European Archives of Paediatric Dentistry : Official Journal of the European Academy of Paediatric Dentistry·C SomaniF S L Wong

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.