Regenerative medicine: a surgeon's perspective.

Journal of Pediatric Surgery
Michael T Longaker

Abstract

More than 200 million incisions are made in the world each year on children and adults. They all end up with a scar unless there is an unusual situation where we are operating on an early gestation fetus. The question is, "why do we not regenerate?" and "why do we always heal with either a 'normal amount of scarring' or, approximately 15% of the time, with a pathologic amount of scarring (hypertrophic scar or keloid)?"

References

Apr 1, 1996·Plastic and Reconstructive Surgery·M W FergusonM T Longaker
Apr 11, 2003·Nature·Stephen M WarrenMichael T Longaker
Dec 24, 2003·Molecular Cell·Kryn StankunasGerald R Crabtree
Apr 13, 2004·Nature Biotechnology·Catherine M CowanMichael T Longaker
May 17, 2007·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Shahram AarabiGeoffrey C Gurtner
May 23, 2007·Nature Biotechnology·Eran SegalMichael D Kuo
Jul 5, 2007·The Journal of Biological Chemistry·Derrick C WanMichael T Longaker
Sep 7, 2007·PLoS Medicine·Shahram AarabiGeoffrey C Gurtner
Nov 22, 2007·Science·Junying YuJames A Thomson

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Citations

May 18, 2011·Meditsinskaia tekhnika·V Iu PlavskiĭA V Mostovnikov
Apr 18, 2014·Expert Review of Neurotherapeutics·William D GrafSaskia K Nagel
Nov 7, 2019·Annals of Plastic Surgery·Kelsey LipmanZhong Zheng
Aug 14, 2020·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Pieter R ZwanenburgMarja A Boermeester

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