PMID: 7661361Sep 1, 1995

Region of epidural blockade determines sympathetic and mesenteric capacitance effects in rabbits

Q H HoganJ P Kampine


The mechanisms producing hemodynamic changes during epidural anesthesia are incompletely understood. The role of capacitance changes in the splanchnic venous bed can be clarified by comparing blocks of differing segmental distributions. Specifically, we speculated that blocks that include the innervation to the mesenteric circulation alter hemodynamics, sympathetic activity, and venous capacitance to a greater extent than blocks without blockade of sympathetic nerves to this critical vascular bed. Rabbits were studied during alpha-chloralose anesthesia and mechanical ventilation. Sympathetic efferent nerve activity to the mesenteric vessels was measured by surgically placed electrodes, and mesenteric vein diameter was measured by videomicroscopy. Heart rate and mean arterial pressure were monitored by intraarterial cannulation. Responses were compared after administration of epidural lidocaine using a dose and catheter level that limited anesthetic to lumbar levels (lumbar group) or thoracic levels (thoracic group). In addition, hemodynamic responses were recorded after thoracolumbar block in animals receiving alpha-chloralose but breathing spontaneously (spontaneous ventilation group) and in awake animals (awake group). Mean a...Continue Reading


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Nov 11, 1998·Acta Anaesthesiologica Scandinavica·Y C KimS C Lee
Apr 9, 2005·European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes·J AdolphsM Schafer
Nov 30, 2000·Critical Care : the Official Journal of the Critical Care Forum·G AcklandM G Mythen
Jul 15, 2009·Critical Care : the Official Journal of the Critical Care Forum·Hendrik FreiseLars G Fischer
Dec 24, 2004·Anesthesia and Analgesia·Hendrik FreiseAndreas W Sielenkämper
Jun 25, 2005·Anesthesia and Analgesia·Shizuko KosugiJ Takeda
Dec 10, 2013·Critical Care : the Official Journal of the Critical Care Forum·Kai A BachmannOliver Mann
Jul 11, 2001·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·A SielenkämperHugo K Van Aken
Sep 28, 2004·Intensive Care Medicine·Andreas W Sielenkämper, Hugo Van Aken
Oct 3, 2006·Current Opinion in Anaesthesiology·N Rolf
Jul 2, 2009·Current Opinion in Anaesthesiology·Hendrik Freise, Lars G Fischer
Apr 2, 1998·Anesthesiology·Q H HoganJ P Kampine
Sep 2, 2000·Anesthesiology·Andreas W SielenkämperHugo Van Aken
Jan 13, 1999·European Journal of Anaesthesiology·G Brodner, Hugo Van Aken
Jun 9, 2009·Burns : Journal of the International Society for Burn Injuries·Fatih UygurCihan Sahin
Jan 18, 2008·ANZ Journal of Surgery·Kamran Zargar-Shoshtari, Andrew G Hill
Apr 14, 2007·Acta Anaesthesiologica Scandinavica·P MicheletJ-P Auffray
Nov 26, 2008·Acta Anaesthesiologica Scandinavica·T LedowskiA Ford
Aug 2, 2006·Acta Anaesthesiologica Scandinavica·J LagunillaS Veiras
Jun 22, 2005·Best Practice & Research. Clinical Anaesthesiology·R Waurick, Hugo Van Aken
Dec 5, 2009·Seminars in Cardiothoracic and Vascular Anesthesia·Zdenek TurekVladimir Cerny
Mar 8, 2006·World Journal of Gastroenterology : WJG·Alp DemiragLeo H Bühler
Jan 12, 2001·Anaesthesia and Intensive Care·B T Veering, M J Cousins
Oct 18, 2005·Journal of Applied Physiology·Philippe P ArbeilleDania M Mohty
Dec 7, 2017·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·P FeltraccoC Ori
Sep 10, 2003·Anesthesiology·Andreas W Sielenkämper, Hugo Van Aken


Nov 1, 1992·Journal of the Autonomic Nervous System·W Jänig, E M McLachlan
Jan 1, 1992·Journal of the Autonomic Nervous System·C DeanJ P Kampine
Aug 1, 1990·Acta Anaesthesiologica Scandinavica·S LundinM Elam
Mar 1, 1988·Journal of Applied Physiology·L B BellJ P Kampine
Jan 1, 1986·Reviews of Physiology, Biochemistry and Pharmacology·R Hainsworth
Aug 1, 1987·Acta Anaesthesiologica Scandinavica·M WattwilS Nordström
Jan 1, 1985·Acta Anaesthesiologica Scandinavica·M BengtssonL A Malmqvist
Dec 1, 1985·Anesthesiology·J O ArndtK D Stühmeier
Mar 1, 1974·Circulation Research·J A Drees, C F Rothe
Nov 1, 1966·Canadian Anaesthetists' Society Journal·P E Otton, E J Wilson
Oct 1, 1983·Physiological Reviews·C F Rothe
May 1, 1965·Acta Physiologica Scandinavica·K FUXE, G SEDVALL

Related Concepts

Arterial Pulse Pressure
Microscopy, Video
Splanchnic Circulation
Adrenergic Fibers
Sympathetic Nervous System
Entire Vein
Muscle Innervation, Function
Body Parts - Epidural

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