Regional and Rural-Urban Differences in the Use of Direct-acting Antiviral Agents for Hepatitis C Virus: The Veteran Birth Cohort

Medical Care
Basile NjeiAmy Justice

Abstract

Veterans with hepatitis C virus (HCV) infection may face geographic obstacles to obtaining treatment. We studied the influence of region and rural versus urban residence on receipt of direct-acting antiretroviral (DAA) medications for HCV. Veterans receiving care within Veterans Affairs Healthcare System born between 1945 and 1965. This is a observational study using national electronic health record data. Receipt of DAAs was defined as ≥1 filled prescription from January 1, 2014 to December 31, 2016. Region (South, Northeast, Midwest, and West) and residence (urban, rural-micropolitan, small rural towns, and isolated rural towns) variables were created using residential zone improvement plan codes and rural-urban commuting area (RUCA) codes. Multivariable models were adjusted for age, race, sex, severity of liver disease, comorbidities, and prior treatment experience. Among 166,353 eligible patients 64,854 received, DAAs. Variation by rural-urban residence depended on region. In unadjusted analyses, receipt varied by rural-urban designations within Midwest, and West regions (P<0.05) but did not vary within the South (P=0.12). Southern rural small town had the lowest incidence of DAA receipt (40.1%), whereas the incidence was 5...Continue Reading

References

Aug 26, 1998·The Journal of Rural Health : Official Journal of the American Rural Health Association and the National Rural Health Care Association·T G HeckmanJ A Kelly
Nov 14, 2001·Archives of Internal Medicine·J P LeighM Schenker
Jul 24, 2002·The Journal of Rural Health : Official Journal of the American Rural Health Association and the National Rural Health Care Association·Claudia L SchurSamuel A Bozzette
Jun 29, 2005·American Journal of Public Health·L Gary HartDenise M Lishner
Apr 12, 2006·The Journal of Rural Health : Official Journal of the American Rural Health Association and the National Rural Health Care Association·Leighton ChanDavid C Goodman
Jul 31, 2008·Health Services Research·Alan N WestAmy E Wallace
Mar 15, 2011·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Lisa I BackusLarry A Mole
Dec 30, 2011·AIDS and Behavior·Michael OhlMary Vaughan-Sarrazin
Jan 20, 2012·The New England Journal of Medicine·Anna S LokClaudio Pasquinelli
Sep 20, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Anne C MoormanUNKNOWN Chronic Hepatitis Cohort Study Investigators
Dec 7, 2013·Journal of Viral Hepatitis·L M HaganR F Schinazi
Dec 18, 2013·Journal of Hepatology·UNKNOWN European Association for Study of Liver
Feb 14, 2015·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Andrew J LeidnerScott D Holmberg
Mar 17, 2015·Annals of Internal Medicine·Mehdi NajafzadehNiteesh K Choudhry
Oct 29, 2015·The Turkish Journal of Gastroenterology : the Official Journal of Turkish Society of Gastroenterology·Veysel TahanJamal A Ibdah
Mar 30, 2016·The American Journal of Gastroenterology·Jessica L MellingerGrace L Su
May 1, 2016·Journal of Hepatology·Souvik SarkarJoseph K Lim
May 2, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Fasiha KanwalSteven M Asch
May 16, 2017·Journal of the American Medical Informatics Association : JAMIA·Ronald George HauserAlex Ryder
Oct 4, 2017·Annals of Internal Medicine·Pamela S BelperioDavid Shulkin

❮ Previous
Next ❯

Citations

Oct 6, 2019·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Kathleen N LyRuth B Jiles
Sep 22, 2020·Military Medical Research·Joseph J BoscarinoJoseph A Boscarino
Sep 4, 2020·Telemedicine Journal and E-health : the Official Journal of the American Telemedicine Association·Ping DuJeah Jung
May 28, 2021·Telemedicine Reports·Ping DuJeah Jung

❮ Previous
Next ❯

Software Mentioned

RUCA
R
SAS

Related Concepts

Related Feeds

Antivirals

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Antivirals (ASM)

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Related Papers

Federal Practitioner : for the Health Care Professionals of the VA, DoD, and PHS
Pamela S BelperioLisa I Backus
The Journal of Rural Health : Official Journal of the American Rural Health Association and the National Rural Health Care Association
Daniel BechtoldKenn B Daratha
© 2022 Meta ULC. All rights reserved