Regional anesthesia and pain management in patients with sleep apnea: can they improve outcomes?

Current Opinion in Anaesthesiology
Crispiana CozowiczStavros G Memtsoudis

Abstract

In several guidelines, regional anesthesia and analgesia have been suggested as safer alternatives for general anesthesia and systemic analgesia for their safety profile in patients suffering from obstructive sleep apnea (OSA). However, the underlying scientific basis is still evolving. The present review is intended to provide an up-to-date account on the question whether the use of regional anesthesia improves outcomes in patients with OSA. A number of studies found favorable effects of regional anesthesia used in patients with OSA, including reduced incidence of major perioperative complications such as the need for mechanical ventilation, reintubation and pulmonary/cardiac complications. No negative effects of regional anesthesia specific to patients with OSA were found. Regional anesthesia was most effective when used as a sole technique, but also carried benefits when added to general anesthesia. The majority of available literature focuses on orthopedic surgery and neuraxial anesthesia. Regional anesthesia can be recommended as a good strategy to treat patients with OSA whenever feasible, as it reduces the incidence of potentially catastrophic perioperative complications. However, the breadth of both surgical and regiona...Continue Reading

References

Apr 25, 2000·World Journal of Surgery·H Kehlet
Apr 20, 2001·The European Respiratory Journal·M A CiscarJ Basterra
Nov 24, 2004·Sleep Medicine Reviews·David R HillmanPeter R Eastwood
Mar 22, 2006·Respirology : Official Journal of the Asian Pacific Society of Respirology·Walter T McNicholas, Silke Ryan
Nov 18, 2010·Anesthesia and Analgesia·Stavros MemtsoudisMadhu Mazumdar
Nov 19, 2011·Journal of Anaesthesiology, Clinical Pharmacology·Saravanan AnkichettyFrances Chung
Feb 2, 2012·HSS Journal : the Musculoskeletal Journal of Hospital for Special Surgery·Spencer S LiuStavros G Memtsoudis
Sep 8, 2012·British Journal of Anaesthesia·R KawA V Hernandez
Apr 6, 2013·Regional Anesthesia and Pain Medicine·Stavros G MemtsoudisMadhu Mazumdar
May 18, 2013·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Ole MathiesenHenrik Kehlet
Oct 26, 2013·Anesthesiology·Frances ChungWeimin Kang
Jan 22, 2014·Anesthesia and Analgesia·Stavros G MemtsoudisMadhu Mazumdar
Dec 3, 2014·Journal of Clinical Anesthesia·Faizi HaiAli A El-Solh
Dec 24, 2014·Anesthesiology·Lorri A LeeKaren B Domino
Apr 22, 2017·Anesthesia and Analgesia·Enoch W K LamJean Wong
Jun 7, 2017·The Journal of Arthroplasty·Syed Y NaqviMohammad R Rasouli
Jul 2, 2017·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Christel A L de RaaffBart A van Wagensveld
Nov 8, 2017·Circulation·Luciano F DragerUNKNOWN INCOSACT Initiative (International Collaboration of Sleep Apnea Cardiovascular Trialists)
Sep 18, 2018·Critical Care Medicine·Ayòtúndé B FadayomiOluwaseun Akeju
Mar 14, 2019·HSS Journal : the Musculoskeletal Journal of Hospital for Special Surgery·Ellen M Soffin, Christopher L Wu

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.