PMID: 3752075Sep 1, 1986Paper

Regional anticoagulation: hemodialysis with hypertonic trisodium citrate

American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
J Von BrechtV S Lim

Abstract

We have developed a simplified method for performing regional citrate anticoagulation during hemodialysis. High ultrafiltration rates and specialized equipment were obviated by the use of a 1.6-mol/L trisodium citrate solution and a standard calcium-containing dialysate. Thirty-six dialyses were performed with this technique on 14 stable and 22 high bleeding risk patients. There was no significant decline in plasma-ionized calcium during citrate dialysis, ie, 3.85 +/- 0.34 mg/dL (mean +/- SE) predialysis, to 3.31 +/- 0.26 postdialysis; furthermore, no patient developed neuromuscular symptoms or evidence of cardiovascular instability from hypocalcemia. Serum sodium rose with this procedure, but not to hypernatremic levels. This method of citrate dialysis is safe and effective during continuous blood flow (double-needle) hemodialysis, and is no more difficult to perform than conventional heparin dialysis. Single-needle (reciprocating blood flow) hemodialysis was successfully performed by the additional use of a calcium-free dialysate and separate calcium chloride infusion (10% calcium chloride), but risks the production of unexpected hypercalcemia.

References

May 1, 1967·Anesthesiology·A N Corbascio, N T Smith
Feb 3, 1983·The New England Journal of Medicine·R V PinnickD A Diederich
Jul 1, 1961·The American Journal of the Medical Sciences·Y MORITAD S HALL
Feb 22, 1962·The New England Journal of Medicine·J P BUNKERA J MURPHY
Apr 16, 1955·Journal of the American Medical Association·J P BUNKERA J MURPHY

❮ Previous
Next ❯

Citations

Feb 1, 1989·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·J W LohrD Diederich
Jun 1, 1997·Kidney International·S SepulvedaS J Schwab
Oct 3, 1999·Kidney International·R HofbauerW Druml
Feb 13, 2002·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Pieter EvenepoelYves Vanrenterghem
Oct 31, 2001·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·R ApsnerW H Hörl
May 4, 2000·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·D J KutsogiannisR T Gibney
Mar 9, 2005·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Robert ApsnerGere Sunder-Plassmann
May 20, 2003·Seminars in Dialysis·Liam F Casserly, Laura M Dember
Dec 10, 1991·Clinical Materials·R Vanholder
Jun 22, 2005·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Jadranka Buturović-PonikvarRafael Ponikvar
Dec 7, 2007·Blood Purification·Jakob GubensekRafael Ponikvar
May 16, 1998·The Annals of Thoracic Surgery·M D WidmannW E Richenbacher
May 13, 2011·Nephron. Clinical Practice·Robert MactierCormac Breen
Nov 4, 2011·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Fuat H SanerThorsten Feldkamp
Apr 10, 2002·Critical Care Medicine·Gabrielle NuthallMichael Seear
Jun 1, 2020·Journal for Immunotherapy of Cancer·Catalin ConstantinescuCiprian Tomuleasa
Jun 2, 2000·Seminars in Dialysis·R Ouseph, R A Ward
Nov 21, 2007·Anaesthesia and Intensive Care·M SchmitzG R Hetzel
Jan 1, 2000·Hemodialysis International·Stephen R AshTodd S Ing
Jul 9, 2008·The International Journal of Artificial Organs·J Buturovic-PonikvarR Ponikvar
Apr 1, 1996·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·M J FlaniganV S Lim

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.

Related Papers

American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
Monika GuptaRose Bukovsky
American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
Pieter EvenepoelYves Vanrenterghem
American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
J W LohrD Diederich
American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
M J FlaniganV S Lim
© 2021 Meta ULC. All rights reserved