Regional blood flow in rats exposed to supralethal doses of whole body x-irradiation

Radiation and Environmental Biophysics
C Watters, G B Gerber

Abstract

Relative blood flow in different organs of the supralethally (3 kR) whole body X-irradiated rat was studied using labeled 15 mu microspheres. Immediately after irradiation blood flow in brain diminishes. From 10 to 20 hrs a phase of increase in blood flowing to many parenchymal organs ensues. A second maximum 45 to 50 hrs and a third one at 60 hrs. In most organs except in brain and liver relative blood flow diminishes before death. The genesis of these changes as signs of a slowly developing shock is discussed.

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Citations

Mar 1, 1982·Acta Physiologica Scandinavica·S LundinM Hallbäck-Nordlander
Jul 1, 1996·European Journal of Drug Metabolism and Pharmacokinetics·C GiachettiR Palumbo
Mar 1, 1983·Scandinavian Journal of Gastroenterology·B Eriksson, L Johnson

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