PMID: 9420805Jul 1, 1995Paper

Regional concordance and discordance between rest thallium 201 and sestamibi imaging for assessing tissue viability: comparison with postrevascularization functional recovery

Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology
P MarzulloA L'Abbate

Abstract

Whether the combined analysis of rest 201Tl and sestamibi uptake provides additional information regarding myocardial viability in patients with coronary artery disease is still to be investigated. To this aim we studied 22 patients with previous myocardial infarction and regional ventricular dysfunction by quantitative rest sestamibi and 201Tl scintigraphy. All patients underwent revascularization, and echocardiography was repeated 11 +/- 2 weeks later. Concordant results were obtained in 80 of 105 dyssynergic segments. Fifty-one segments showed normal and 29 abnormal activity. Follow-up echocardiography showed increased wall motion contractility in 76% of segments with maintained 201Tl and sestamibi uptake and in only 17% of segments characterized by subthreshold activities. Twenty-five segments, or 24%, showed sestamibi/201Tl mismatch. Eleven of 12 segments with normal sestamibi/abnormal 201Tl activity did not improve after revascularization, whereas 11 of 13 segments with abnormal sestamibi but normal 201Tl showed postoperative improvement of regional wall motion. In patients with previous myocardial infarction, sestamibi and 201Tl showed concordant results in most segments. However, in segments with mismatch a maintained s...Continue Reading

References

Dec 1, 1989·Journal of the American College of Cardiology·V DilsizianC A Boucher
Dec 1, 1989·Journal of the American College of Cardiology·T P RoccoC A Boucher
Dec 1, 1989·Journal of the American College of Cardiology·J Machac
Jan 1, 1989·The American Journal of Cardiology·G A Diamond
Dec 1, 1988·Journal of the American College of Cardiology·H KiatJ Friedman

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Citations

May 28, 2008·European Journal of Nuclear Medicine and Molecular Imaging·Kenichi NakajimaHitonobu Tomoike
Jun 19, 2013·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Kevin C Allman
Jul 11, 2000·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·A CuocoloM Salvatore
Nov 5, 1999·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·J F BatistaE V Garcia
Jul 17, 2001·Nuclear Medicine Communications·J M GonzálezUNKNOWN Spanish Working Group of Nuclear Cardiology
Aug 11, 2006·Current Opinion in Cardiology·Rajan A G Patel, George A Beller
Feb 8, 2005·Echocardiography·Deval Mehta, Ami E Iskandrian

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