PMID: 3745053Aug 1, 1986Paper

Regional control of local airway heat and water vapor losses

Journal of Applied Physiology
L M Hanna, P W Scherer

Abstract

The regulation of local heat and water vapor losses along the respiratory tract is examined based on a theoretical model of respiratory air conditioning and physiological data. The theoretical model is a quasi-steady one-dimensional model descriptive of the localized process of heat and water transport within the airways. During nasal breathing the model is most sensitive to the following two parameters: 1) the gradient of blood temperature along the airway wall and 2) the nasal air space volume. Thermoregulatory control of these two factors within the primary conditioning region, the upper airway, establishes the overall respiratory heat and water loss. Upper airway thermoregulation, however, also effects the heat and water demands placed on the secondary conditioning region, the tracheobronchial airways. Similar to the upper airway, the tracheobronchial airway wall temperature varies in response to changing demands. The bronchial circulation is shown to provide a major source of heat within the first several bronchial generations where the greatest heat and water fluxes within the lung are predicted to occur. Control of the bronchial blood flow may therefore directly influence the bronchoconstrictive response in asthmatics.

Citations

Jan 3, 1996·Journal of Aerosol Medicine : the Official Journal of the International Society for Aerosols in Medicine·E M Wagner
Oct 2, 2007·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Nelson Bergonse NetoGilberto da Fontoura Rey Bergonse
Feb 21, 2008·American Journal of Rhinology·Thomas KappeTilman Keck
Mar 1, 1989·Acta Physiologica Scandinavica·R MatranJ M Lundberg
Jan 1, 1988·Annals of Biomedical Engineering·M E TsuM P Hlastala
Jul 14, 2004·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A RozsasiT Keck
Nov 12, 2005·Journal of Applied Physiology·Joseph C AndersonMichael P Hlastala
Jul 12, 2007·American Journal of Rhinology·Ajnacska RozsasiTilman Keck
Mar 26, 2010·Annals of Biomedical Engineering·Joseph C Anderson, Michael P Hlastala
Apr 25, 2015·Biomedical Engineering Online·David E WhiteRoy J Nates
Aug 2, 2014·Annals of Biomedical Engineering·Dan WuChing-Long Lin
May 25, 2005·Annals of Biomedical Engineering·Sara NaftaliDavid Elad
Jun 16, 2011·Journal of Aerosol Medicine and Pulmonary Drug Delivery·Helene HolmgrenEvert Ljungström

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