PMID: 2472558Jan 1, 1989Paper

Regional cortical blood flow during extra-intracranial bypass surgery in young patients with moyamoya disease

Neurologia Medico-chirurgica
S TakeuchiI Nagata


Regional cortical blood flow (rCBF) was measured with a thermal diffusion flow probe in 14 cortical regions of 12 young patients with moyamoya disease before and after completion of superficial temporal-middle cerebral artery anastomosis. The prebypass rCBF value was low in most patients, especially in the frontal regions. On temporary occlusion of the cortical artery during the surgical procedure, no significant drop in rCBF occurred. rCBF increased immediately after anastomosis in all but one region and continued to increase for 5-10 minutes in four of the eight regions measured. In the other four regions, rCBF declined gradually after the initial increase, and the final increase was slight. The average increase in rCBF was significant at 1-2 minutes and at 5-10 minutes after anastomosis. However, the latter increase did not bring the flow into the normal range. It may be that the initial increase in postbypass rCBF is determined solely by the pressure gradient between the donor and recipient arteries, and that subsequent rCBF is controlled by other factors within the brain. In one patient who underwent double anastomoses to the frontal and temporal lobes, neither anastomosis increased rCBF in the non-corresponding lobe to re...Continue Reading

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.


Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.