Abstract
Hypoplastic left heart syndrome (HLHS) is a highly resource-intensive diagnosis. Geographic variation in cost and length of stay (LOS) in HLHS is not well described. Neonates diagnosed with HLHS between 2000 and 2012 were identified using the Kids' Inpatient Database. Hospitalizations were stratified into two groups: (1) birth and (2) secondary. United States regional differences in hospital charges and LOS were compared using adjusted linear regression. Of 2431 birth hospitalizations, 449 neonates (18.5%) died while inpatient and mortality rates differed by region (p = 0.02). After birth, 40.5% (n = 985) of neonates were transferred; transfers were most common in the Midwest (p < 0.0001). Adjusted average LOS was shortest in the West and longest in the South (26.1 days; 95% CI 24.0, 35.1 vs. 34.9 days; 95% CI 31.8, 38.1). Average adjusted charges were lowest in the Northeast ($324,600; 95% CI $271,400, $377,900) and highest in the West ($400,500; 95% CI $346,700, $454,300, p = 0.05). Among 1895 secondary hospitalizations, 24.9% of neonates died as inpatients, and the average adjusted LOS was shortest in the West (26.8 days; 95% CI 23.9, 29.7) and longest in the South (38.5 days; 95% CI 34.4, 42.4). Average adjusted charges wer...Continue Reading
References
Jan 1, 1985·American Journal of Epidemiology·C FerenczJ W Downing
Jun 27, 2002·Journal of the American College of Cardiology·Julien I E Hoffman, Samuel Kaplan
Mar 25, 2004·Birth Defects Research. Part A, Clinical and Molecular Teratology·Christine E CronkD Gail McCarver
Oct 6, 2006·Birth Defects Research. Part A, Clinical and Molecular Teratology·Quanhe YangMargaret A Honein
May 15, 2007·Circulation Research·Paul Grossfeld
Apr 2, 2008·Congenital Heart Disease·Oscar J BenavidezKathy J Jenkins
Jun 7, 2008·The Journal of Pediatrics·Brent M GordonRuey-Kang Chang
Aug 30, 2008·The Annals of Thoracic Surgery·Karl F WelkeRoss M Ungerleider
May 28, 2010·The New England Journal of Medicine·Richard G OhyeUNKNOWN Pediatric Heart Network Investigators
Aug 21, 2010·The Journal of Thoracic and Cardiovascular Surgery·Jean A BallwegSarah Tabbutt
Apr 21, 2011·Circulation. Cardiovascular Quality and Outcomes·Sara K PasqualiJennifer S Li
Oct 12, 2011·Pediatrics·Peter N DeanHoward P Gutgesell
Feb 26, 2014·Pediatrics·Sara K PasqualiJennifer S Li
Jul 20, 2014·The Annals of Thoracic Surgery·S Adil HusainMarshall L Jacobs
Oct 1, 2014·The Journal of Thoracic and Cardiovascular Surgery·Tara KaramlouChristopher A Caldarone
Oct 27, 2015·Orphanet Journal of Rare Diseases·David A DanfordShelby Kutty
Dec 31, 2015·Cardiology in the Young·Kimberly E McHughMark A Scheurer
Oct 26, 2016·Circulation·Richard G OhyeYves D'Udekem
Citations
Jan 30, 2020·Circulation·Salim S ViraniUNKNOWN American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee
Jul 22, 2020·Journal of the American Heart Association·Michael L O'ByrneLaura Mercer-Rosa
Apr 28, 2020·Pediatric Cardiology·Cynthia L GongRoberta G Williams
Jan 28, 2021·Circulation·Salim S ViraniUNKNOWN American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee