Regional differences of cerebral blood flow in the preterm infant

European Journal of Pediatrics
O BaenzigerH U Bucher

Abstract

The purpose of our study was to evaluate the regional distribution of the resting cerebral blood flow (CBF) pattern in preterm neonates. Sixty-eight preterm babies with a gestational age of less than 34 weeks and a birth weight of less than 1500 g were enrolled into the study. The CBF was measured by the noninvasive intravenous 133Xenon method at three different times. Depending on the age we classified our measurements into three groups. Group 1: measurement between 2-36 h (n = 46). Group 2: measurement between 36-108 h (n = 39). Group 3: measurement between 108-240 h (n = 41). In all three groups CBF was significantly lower in the occipital region than in the frontal and parietal regions (group 1: frontal region 12.8 +/- 3.5 ml/100 g/min, parietal region 12.8 +/- 3.9 ml/100 mg/min, and occipital region 11.6 +/- 3.18 ml/100 g/min; group 2: frontal region 15.4 +/- 4.2 ml/100 g/min, parietal region 15.3 +/- 4.1 ml/100 g/min, and occipital region 13.4 +/- 3.5 ml/100 g/min; group 3: frontal region 14.6 +/- 3.6 ml/100 g/min, parietal region 14.6 +/- 3.2 ml/100 g/min, and occipital region 12.8 +/- 2.7 ml/100 g/min.). CBF did not differ between the left and the right hemispheres in either of the three measured regions. No gradient wa...Continue Reading

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Citations

Sep 27, 2002·Early Human Development·Kou IchihashiMariko Momoi
Aug 9, 2003·Pediatric Research·Dulip JayasingheMalcolm I Levene
Mar 6, 2004·Annals of the New York Academy of Sciences·Bradley S Peterson
Mar 15, 2006·Ultrasound in Medicine & Biology·Costantino RomagnoliPatrizia Papacci
Feb 12, 1998·Pediatric Research·K Børch, G Greisen

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