Regional relative blood volume MR maps of meningiomas before and after partial embolization

Journal of Computer Assisted Tomography
R BrueningM Reiser

Abstract

Our goal was to evaluate the role of relative blood volume (rBV) measurements in monitoring the embolization effect in meningiomas by using maps of susceptibility-weighted first pass MR data. Eighteen examinations of nine patients before and following partial embolization were performed on a 1.5 T scanner. Embolization was achieved by injection of particles (45-150 microns). During dynamic imaging a bolus (0.2 mmol/kg) of gadopentetate dimeglumine was injected. The tumor rBV/gray matter rBV ratio was 3.11 +/- 1.40 for untreated tumors and 0.12 +/- 0.09 for successfully embolized tumors. The regional rBV in embolized meningiomas was significantly lower than that in untreated meningiomas (t test, p < 0.001). Vital tumor tissue showed positive enhancement in T1 and high rBV; nonvital tissue lacked T1 enhancement and bolus effect in the first pass, thus leading to low or missing rBV values. However, we also observed lack of bolus formation despite T1 enhancement (6/9 postembolization regions), possibly due to slow collateral flow. One of the patients treated with embolization bled during surgery. Maps of relative regional cerebral BV provide hemodynamic information in meningiomas and monitor the treatment effect of embolization in ...Continue Reading

References

Aug 1, 1992·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·P GowlandJ Firth
Jan 1, 1992·Neuroradiology·T TeradaN Komai
Jun 1, 1991·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·B R RosenK K Kwong
May 1, 1990·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·B R RosenT J Brady
Jun 1, 1990·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·J W BelliveauT J Brady
Jul 1, 1994·AJR. American Journal of Roentgenology·M MaedaT Kubota
May 1, 1994·Journal of Computer Assisted Tomography·F GückelM Georgi

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Citations

Apr 26, 2003·European Journal of Radiology·Kazuhiro TsuchiyaJunichi Hachiya
Apr 28, 2012·Journal of Neurointerventional Surgery·E Jesus DuffisUNKNOWN Society for Neurointerventional Surgery
Sep 26, 2007·AJNR. American Journal of Neuroradiology·S K EllikaT Mikkelsen
Sep 10, 2004·Journal of Neuroradiology. Journal De Neuroradiologie·R H WuM Reiser
Mar 18, 2006·Neuroimaging Clinics of North America·Soonmee Cha
Feb 11, 2004·Magnetic Resonance Imaging Clinics of North America·Soonmee Cha
Mar 29, 2005·Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban·Renhua WuMaximilian Reiser

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