PMID: 18183794Jan 11, 2008Paper

Regional skeletal bone deficit in female adolescents with anorexia nervosa: influence of the degree of malnutrition and weight recovery in a two year longitudinal study

Journal of Pediatric Endocrinology & Metabolism : JPEM
María Teresa García-De AlvaroJesús Argente

Abstract

To analyze changes in bone mineral density (BMD) and the effect of weight recovery on the restoration of bone mass in adolescent females with anorexia nervosa (AN) with moderate malnutrition. We evaluated lumbar and femoral BMD in 27 females with restrictive AN with malnutrition and amenorrhea for over (M+PA) or less than (M+SA) one year and 12 with normal nutrition and amenorrhea for over one year (N+PA) followed for 24 months. BMI remained below -1.5 SD in M+PA and increased at 24 months in M+SA. M+PA had low lumbar and femoral neck BMD at diagnosis, decreasing at 24 months. Lumbar BMD in N+PA and M+SA was reduced, with an increase in M+SA at 24 months. Moderate malnutrition in AN induces loss of bone mass at the lumbar and femoral levels. Weight gain and resumption of menses increases bone mass, especially in the lumbar spine.

References

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Sep 5, 2002·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Thierry Thomas, Bartolome Burguera
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Citations

Jul 10, 2010·Child and Adolescent Psychiatry and Mental Health·Ulrike Me SchulzeClaudia Mehler-Wex
Aug 28, 2015·The International Journal of Eating Disorders·Madhusmita MisraDebra K Katzman
Jul 8, 2011·The Journal of Clinical Endocrinology and Metabolism·Alison M Boyce, Rachel I Gafni

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Anorexia Nervosa

Anorexia nervosa (AN) is a psychiatric condition characterized by severe weight loss and secondary problems associated with malnutrition. Here is the latest research on AN.