Regional variation of premature mortality in Ontario, Canada: a spatial analysis

Population Health Metrics
Emmalin BuajittiLaura C Rosella

Abstract

Premature mortality is a meaningful indicator of both population health and health system performance, which varies by geography in Ontario. We used the Local Health Integration Network (LHIN) sub-regions to conduct a spatial analysis of premature mortality, adjusting for key population-level demographic and behavioural characteristics. We used linked vital statistics data to identify 163,920 adult premature deaths (deaths between ages 18 and 74) registered in Ontario between 2011 and 2015. We compared premature mortality rates, population demographics, and prevalence of health-relevant behaviours across 76 LHIN sub-regions. We used Bayesian hierarchical spatial models to quantify the contribution of these population characteristics to geographic disparities in premature mortality. LHIN sub-region premature mortality rates ranged from 1.7 to 6.6 deaths per 1000 per year in males and 1.2 to 4.8 deaths per 1000 per year in females. Regions with higher premature mortality had fewer immigrants and higher prevalence of material deprivation, excess body weight, inadequate fruit and vegetable consumption, sedentary behaviour, and ever-smoked status. Adjusting for all variables eliminated close to 90% of geographic variation in prematu...Continue Reading

References

Jan 1, 1991·Statistics in Medicine·A Mollie, S Richardson
Aug 29, 2000·Statistics in Medicine·A B LawsonF Divino
Jan 12, 2001·Journal of Epidemiology and Community Health·K E Pickett, M Pearl
Feb 24, 2001·American Journal of Epidemiology·H BosmaJ P Mackenbach
Apr 12, 2001·Australian and New Zealand Journal of Public Health·M Tobias, G Jackson
Sep 29, 2004·American Journal of Public Health·Mark S Eberhardt, Elsie R Pamuk
Jul 1, 2006·Biostatistics·Jon Wakefield
Dec 1, 2006·Journal of Health & Social Policy·Adela Beckerman
Mar 17, 2007·Health Services Research·Julia C Prentice, Steven D Pizer
Aug 26, 2009·Bulletin of the World Health Organization·Gerd Gigerenzer
May 16, 2012·Health & Social Care in the Community·Kerry KuluskiAudrey Laporte
Feb 20, 2013·Artificial Intelligence in Medicine·Martijn LappenschaarStefan Visscher
Apr 8, 2017·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Jack V TuUNKNOWN Cardiovascular Health in Ambulatory Care Research Team (CANHEART)

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Citations

May 29, 2020·Canadian Journal of Public Health = Revue Canadienne De Santé Publique·Laura C RosellaAdalsteinn Brown
Oct 24, 2019·International Journal of Environmental Research and Public Health·Silvia Megyesiova, Vanda Lieskovska
Dec 4, 2021·Scientific Reports·Anaïs LadoyStéphane Joost

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