Regional variations in glia and neuropil within the hypothalamic ventromedial nucleus

The Journal of Comparative Neurology
M Van Houten, J R Brawer

Abstract

The normal fine structure of glia and neuropil in the various regional subdivisions of the hypothalamic ventromedial nucleus in the adult male albino rat is described in this report. Although most HVM astrocytes throughout the nucleus appear ordinary in cytology, certain astrocytes found in the posterior ventrolateral subdivision of the nucleus appear somewhat reactive, in that they contain numerous thick fascicles of gliofibrils and pleomorphic dense bodies. The processes of these reactive astrocytes elaborate multiple, concentric lamellae which encapsulate small, round, pyknotic masses (probably degenerate axonal elements). These degenerate profiles, which are greatly outnumbered by normal HVM boutons, may represent synaptic contacts that deteriorate spontaneously in the normal adult HVM. Other signs of spontaneous degeneration occurring within this neuropil include the occasional presence of large masses of necrotic debris which appear engulfed by microglia. These findings suggest the presence in the normal adult HVM neuropil of a low-grade degenerative process with attendant gliosis, which is topographically centered about the posterior ventrolateral region of the nucleus. Regions of neuropil containing degenerate boutons a...Continue Reading

References

Oct 15, 1976·The Journal of Comparative Neurology·C B SaperW M Cowan
Jan 1, 1976·Current Topics in Molecular Endocrinology·G Pelletier
Mar 1, 1978·The Journal of Comparative Neurology·M Van Houten, J R Brawer
Aug 1, 1977·The Journal of Comparative Neurology·R L McBride, J Sutin
Jan 1, 1976·Journal of Neuroscience Research·L L Bernardis, J K Goldman
Jan 1, 1975·Journal of Neuropathology and Experimental Neurology·J M Andrews
Jun 1, 1975·Endocrinology·M BrownsteinJ S Kizer
Jan 28, 1976·Cell and Tissue Research·F H Güldner
Jun 15, 1976·The Journal of Comparative Neurology·N Lemkey-JohnstonW A Reynolds
Apr 1, 1969·Brain Research·L Heimer, W J Nauta
May 30, 1973·Brain Research·O E Millhouse
Jul 19, 1974·Science·M J BrownsteinR D Utiger
Jun 1, 1971·The Journal of Cell Biology·K M YamadaN K Wessells
Jun 28, 1973·The New England Journal of Medicine·J B Martin
Dec 31, 1973·Zeitschrift für Zellforschung und mikroskopische Anatomie·J BarryP Poulain
Oct 1, 1973·The Journal of Comparative Neurology·J M Kerns, E J Hinsman
May 26, 1972·Brain Research·G B MakaraK M Spyer
Nov 1, 1967·The American Journal of Anatomy·T L Lentz
Jan 1, 1967·Zeitschrift für Zellforschung und mikroskopische Anatomie·E Mugnaini, P F Forstronen
Jan 1, 1968·Journal of Neuropathology and Experimental Neurology·A N D'Agostino, S Maruyama
Jan 1, 1968·Zeitschrift für Zellforschung und mikroskopische Anatomie·A Pellegrino de Iraldi, E De Robertis
Jul 1, 1968·The Journal of Comparative Neurology·M P De Cerro, R S Snider
Jan 1, 1969·Journal of Neurophysiology·J T Murphy, L P Renaud
Apr 1, 1969·Brain Research·G K AghajanianM H Sheard
Oct 1, 1969·The Journal of Comparative Neurology·G B Dunkerley, D Duncan
Sep 1, 1965·The American Journal of Physiology·P W HanA C Liu
Nov 1, 1957·The Journal of Endocrinology·G C KENNEDY

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Citations

Aug 19, 1991·Brain Research. Developmental Brain Research·L D Pozzo Miller, A Aoki
Nov 1, 1981·Behavioural Brain Research·J Panksepp, J Rossi
Aug 5, 2014·European Journal of Pharmacology·J G VeeningB Olivier
Sep 18, 1995·The Journal of Comparative Neurology·A ReichenbachJ Schnitzer
Apr 1, 1992·Cellular and Molecular Neurobiology·L D Pozzo Miller, A Aoki

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