Regional ventricular performance and exercise training in children and young adults after repair of tetralogy of Fallot: randomized controlled pilot study

Circulation. Cardiovascular Imaging
Nienke DuppenL Kapusta

Abstract

Public-health guidelines recommend patients with congenital heart disease to exercise. Studies have shown that patients with congenital heart disease can improve physical exercise capacity. The effect of training on regional ventricular performance has hardly been studied. We performed a pilot study to assess whether an exercise training program would result in adverse changes of regional ventricular performance in patients with corrected tetralogy of Fallot. Multicenter prospective randomized controlled pilot study in patients with tetralogy of Fallot aged 10 to 25 years. A 12-week standardized aerobic dynamic exercise training program (3 one-hour sessions per week) was used. Pre- and post-training cardiopulmonary exercise tests, MRI, and echocardiography, including tissue-Doppler imaging, were performed. Patients were randomized to the exercise group (n=28) or control group (n=20). One patient in the exercise group dropped out. Change in tissue-Doppler imaging parameters was similar in the exercise group and control group (change in right ventricle free wall peak velocity E' exercise group, 0.8±2.6 cm/s; control group, 0.9±4.1; peak velocity A' exercise group, 0.4±2.4 m/s; control group 4.6±18.1 cm/s). This randomized control...Continue Reading

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Citations

Jun 24, 2015·Clinics in Sports Medicine·Silvana Molossi, Michelle Grenier
Jun 23, 2016·International Journal of Cardiology·Pablo ÁvilaPaul Khairy
Jan 28, 2017·La Presse médicale·Pascal AmedroSophie Guillaumont
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Dec 6, 2017·Congenital Heart Disease·Camilla SandbergBengt Johansson
Oct 17, 2020·Indian Journal of Thoracic and Cardiovascular Surgery : Official Organ, Association of Thoracic and Cardiovascular Surgeons of India·Smita Mishra, Rajesh Sharma
Dec 8, 2020·The Annals of Thoracic Surgery·Derek L TranRachael Cordina

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