Regions of the MPFC differentially tuned to social and nonsocial affective evaluation

Cognitive, Affective & Behavioral Neuroscience
Lasana T HarrisSusan T Fiske

Abstract

The medial prefrontal cortex (MPFC) reliably activates in social cognition and reward tasks. This study locates distinct areas for each. Participants made evaluative (positive/negative) or social (person/not a person) judgments of pictured positive or negative people and objects in a slow event-related design. Activity in an anterior rostral region (arMPFC) was significantly greater for positive than for negative persons but did not show a valence effect for objects, and this was true regardless of the judgment task. This suggests that the arMPFC is tuned to social valence. Interestingly, however, no regions of the MPFC were found to be responsive to social information independently of valence. A region-of-interest analysis of the para-anterior cingulate cortex (pACC), previously implicated in reward processing, demonstrated sensitivity to the valence of all stimuli, whether persons or objects, across tasks. Affective evaluation may be a general function of the MPFC, with some regions being tuned to more specific domains of information (e.g., social) than are others.

Citations

Jul 28, 2011·European Archives of Psychiatry and Clinical Neuroscience·Evelina HaralanovaKristina Hennig-Fast
Dec 3, 2008·Social Cognitive and Affective Neuroscience·Hal Ersner-HershfieldBrian Knutson
Mar 24, 2009·Social Cognitive and Affective Neuroscience·Wouter van den BosEveline A Crone
Sep 8, 2011·Social Cognitive and Affective Neuroscience·Emiliana R Simon-ThomasDacher J Keltner
Jul 31, 2012·Social Cognitive and Affective Neuroscience·Elisa CiaramelliGiuseppe di Pellegrino
Jul 12, 2011·Annual Review of Psychology·Sarah E Hampson
Jan 10, 2016·NeuroImage·Prathik KiniJoshua W Brown
May 7, 2013·Psychiatry Research·Olivia A Bjorkquist, Ellen S Herbener
Jan 1, 2011·Research in Organizational Behavior·Susan T Fiske, Eugene Borgida
Jun 30, 2009·NeuroImage·Michael G HardinMonique Ernst
Jan 5, 2010·Evolution and Human Behavior : Official Journal of the Human Behavior and Evolution Society·Heather A RuppJulia R Heiman
Jul 8, 2009·Annals of the New York Academy of Sciences·Berna GüroğluEveline A Crone
Mar 23, 2012·The British Journal of Social Psychology·Susan T Fiske
Oct 21, 2015·Frontiers in Psychology·Glenn R FoxAntonio Damasio
Apr 17, 2016·Schizophrenia Research·Olivia A BjorkquistEllen S Herbener
Mar 17, 2010·Neuropsychologia·Harold W KoenigsbergLarry J Siever
Mar 13, 2014·Developmental Cognitive Neuroscience·Patricia Z TanJennifer S Silk
Jun 21, 2015·Brain and Cognition·Tamas BereczkeiAnita Deak
Jan 1, 2011·Zeitschrift Für Psychologie·Lasana T Harris, Susan T Fiske
Apr 11, 2015·Frontiers in Psychology·Joel S PetermanSohee Park
Sep 23, 2014·NeuroImage·Laurens Van der CruyssenFrank Van Overwalle
Jun 18, 2016·Frontiers in Neuroscience·Tehila Eilam-StockJin Fan
Aug 16, 2016·Social Cognitive and Affective Neuroscience·I Stephanie VezichMatthew D Lieberman
Nov 24, 2012·Personality and Social Psychology Review : an Official Journal of the Society for Personality and Social Psychology, Inc·Thomas F Denson
Jul 21, 2017·Perspectives on Psychological Science : a Journal of the Association for Psychological Science·Susan T Fiske
Aug 27, 2017·Hippocampus·Alison MontagrinDaniela Schiller
Mar 1, 2019·Scientific Reports·Jeroen DelplanqueFrank Van Overwalle
Sep 9, 2020·Brain Imaging and Behavior·Maria ArioliNicola Canessa
Sep 27, 2019·Frontiers in Psychology·Simon Ciranka, Wouter van den Bos
Feb 21, 2018·Social Cognitive and Affective Neuroscience·Xi YangChristian E Waugh
Jul 4, 2021·Neuroscience and Biobehavioral Reviews·Damiano TerenziSoyoung Q Park

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